S Sierro
Overview
Explore the profile of S Sierro including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
356
Followers
0
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Recent Articles
1.
Lopez-Granados E, Stacey M, Kienzler A, Sierro S, Willberg C, Fox C, et al.
Clin Exp Immunol
. 2014 Aug;
178(3):470-82.
PMID: 25079909
Mutations in the X-linked inhibitor of apoptosis (XIAP) gene have been associated with XLP-like disease, including recurrent Epstein-Barr virus (EBV)-related haemophagocytic lymphohystiocytosis (HLH), but the immunopathogenic bases of EBV-related disease...
2.
Esparza J, Miquelez S, Gonzalez A, Rubio A, Manso E, Sierro S, et al.
Radiologia
. 2008 Feb;
50(1):61-6.
PMID: 18275791
Objective: To describe a method of calculating and registering the dose of radiation used in Pamplona County in pediatric examinations, and to show the results obtained one year after its...
3.
Betts G, Twohig J, van den Broek M, Sierro S, Godkin A, Gallimore A
Br J Cancer
. 2007 Jun;
96(12):1849-54.
PMID: 17565340
Burnet proposed in the 1950's that the immune system is engaged in identifying and destroying abnormal cancerous cells. This process, termed immune surveillance, has been at the centre of intense...
4.
Komatsu H, Sierro S, V Cuero A, Klenerman P
Clin Exp Immunol
. 2003 Sep;
134(1):9-12.
PMID: 12974748
MHC class I-peptide tetrameric complexes ('tetramers') have revolutionized the study of antiviral CD8+ T cell responses. They allow accurate quantification of immune responses ex vivo independent of function, with high...
5.
Deletion of the CD4 silencer element supports a stochastic mechanism of thymocyte lineage commitment
Leung R, Thomson K, Gallimore A, Jones E, van den Broek M, Sierro S, et al.
Nat Immunol
. 2001 Nov;
2(12):1167-73.
PMID: 11694883
The mechanism of T cell lineage commitment remains controversial; to examine it we deleted the CD4-silencer element in the germ line of a mouse using a combination of gene targeting...
6.
Ochsenbein A, Sierro S, Odermatt B, Pericin M, Karrer U, Hermans J, et al.
Nature
. 2001 Jun;
411(6841):1058-64.
PMID: 11429607
The vertebrate immune system has evolved to protect against infections that threaten survival before reproduction. Clinically manifest tumours mostly arise after the reproductive years and somatic mutations allow even otherwise...
7.
Maloy K, Erdmann I, Basch V, Sierro S, Kramps T, Zinkernagel R, et al.
Proc Natl Acad Sci U S A
. 2001 Mar;
98(6):3299-303.
PMID: 11248073
Although DNA vaccines have been shown to elicit potent immune responses in animal models, initial clinical trials in humans have been disappointing, highlighting a need to optimize their immunogenicity. Naked...
8.
Ochsenbein A, Pinschewer D, Sierro S, Horvath E, Hengartner H, Zinkernagel R
Proc Natl Acad Sci U S A
. 2000 Nov;
97(24):13263-8.
PMID: 11069289
Memory is a hallmark of immunity. Memory carried by antibodies is largely responsible for protection against reinfection with most known acutely lethal infectious agents and is the basis for most...