S Ranil Wickramasinghe
Overview
Explore the profile of S Ranil Wickramasinghe including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
174
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Recent Articles
1.
Hao X, Horax R, Wickramasinghe S, Qian X
J Chromatogr B Analyt Technol Biomed Life Sci
. 2025 Feb;
1255:124499.
PMID: 39954487
A novel multi-modal anion exchange (MMAEX) membrane with both electrostatic and hydrophobic interaction moieties was developed for the separation of full and empty AAV2 capsids with only slight differences in...
2.
Regmi C, Kshetri Y, Kshetri Y, Wickramasinghe S
Nanotechnology
. 2025 Jan;
36(13).
PMID: 39883952
Over the past few decades, significant efforts have been dedicated to advancing technologies for the removal of micropollutants from water. Achieving complete pure water with a single treatment process is...
3.
Regmi C, Kshetri Y, Wickramasinghe S
Membranes (Basel)
. 2024 Jul;
14(7).
PMID: 39057668
The development of an ideal membrane for membrane distillation (MD) is of the utmost importance. Enhancing the efficiency of MD by adding nanoparticles to or onto a membrane's surface has...
4.
Zhang D, Wickramasinghe S, Zydney A, Smelko J, Loman A, Wheeler A, et al.
Biotechnol Prog
. 2024 Mar;
40(4):e3453.
PMID: 38477450
Chinese hamster ovary (CHO) cells are among the most common cell lines used for therapeutic protein production. Membrane fouling during bioreactor harvesting is a major limitation for the downstream purification...
5.
Haseli M, Pinzon-Herrera L, Hao X, Wickramasinghe S, Almodovar J
Langmuir
. 2023 Nov;
39(46):16472-16483.
PMID: 37944116
The immunomodulatory potential of human mesenchymal stromal cells (hMSCs) can be boosted when exposed to interferon-gamma (IFN-γ). While pretreating hMSCs with IFN-γ is a common practice to enhance their immunomodulatory...
6.
Sundar V, Zhang D, Qian X, Wickramasinghe S, Smelko J, Carbrello C, et al.
Biotechnol Prog
. 2023 Feb;
39(3):e3336.
PMID: 36825399
Alternating tangential flow filtration (ATF) has become one of the primary methods for cell retention and clarification in perfusion bioreactors. However, membrane fouling can cause product sieving losses that limit...
7.
Chen S, Xu W, Cai K, Ferreira G, Wickramasinghe S, Qian X
J Chromatogr B Analyt Technol Biomed Life Sci
. 2022 Sep;
1210:123449.
PMID: 36148766
Mobile and stationary phase factors were investigated in order to identify conditions for effective capture of minute virus of mice (MVM), a potential adventitious contaminant in biomanufacturing, using anion exchange...
8.
Isu S, Qian X, Zydney A, Wickramasinghe S
Bioengineering (Basel)
. 2022 Apr;
9(4).
PMID: 35447715
Regulatory authorities place stringent guidelines on the removal of contaminants during the manufacture of biopharmaceutical products. Monoclonal antibodies, Fc-fusion proteins, and other mammalian cell-derived biotherapeutics are heterogeneous molecules that are...
9.
Chu L, Wickramasinghe S, Qian X, Zydney A
Membranes (Basel)
. 2022 Mar;
12(3).
PMID: 35323774
One major challenge in the development of nanoparticle-based therapeutics, including viral vectors for the delivery of gene therapies, is the development of cost-effective purification technologies. The objective of this study...
10.
Sengupta A, Jebur M, Kamaz M, Wickramasinghe S
Membranes (Basel)
. 2022 Jan;
12(1).
PMID: 35054586
Water is a very valuable natural resource. As the demand for water increases the presence of emerging contaminants in wastewater has become a growing concern. This is particularly true when...