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S R Heckbert

Explore the profile of S R Heckbert including associated specialties, affiliations and a list of published articles. Areas
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Articles 91
Citations 2371
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Recent Articles
1.
Siland J, Geelhoed B, Roselli C, Wang B, Lin H, Weiss S, et al.
PLoS One . 2022 May; 17(5):e0268768. PMID: 35594314
Background: Both elevated and low resting heart rates are associated with atrial fibrillation (AF), suggesting a U-shaped relationship. However, evidence for a U-shaped causal association between genetically-determined resting heart rate...
2.
Harding B, Whitney B, Nance R, Ruderman S, Crane H, Burkholder G, et al.
BMC Infect Dis . 2020 Mar; 20(1):238. PMID: 32197585
Background: Anemia is common among people living with HIV infection (PLWH) and is associated with adverse health outcomes. Information on risk factors for anemia incidence in the current antiretroviral therapy...
3.
de las Fuentes L, Sung Y, Sitlani C, Avery C, Bartz T, De Keyser C, et al.
Pharmacogenomics J . 2019 Dec; 20(3):482-493. PMID: 31806883
Hypertension (HTN) is a significant risk factor for cardiovascular morbidity and mortality. Metabolic abnormalities, including adverse cholesterol and triglycerides (TG) profiles, are frequent comorbid findings with HTN and contribute to...
4.
Folsom A, Lutsey P, Heckbert S, Poudel K, Basu S, Hoogeveen R, et al.
J Thromb Haemost . 2018 Jul; 16(10):1964-1972. PMID: 30007116
Summary: Background We previously showed that participants in the population-based Atherosclerosis Risk in Communities (ARIC) cohort with elevated levels of blood biomarkers of inflammation or cardiac disease were at increased...
5.
Garg P, Biggs M, Kaplan R, Kizer J, Heckbert S, Mukamal K
Nutr Metab Cardiovasc Dis . 2018 Apr; 28(7):716-721. PMID: 29615289
Background And Aims: Existing literature in individuals without diabetes has not demonstrated a relationship between IR and incident AF; however, data are limited and only fasting glucose measures of IR...
6.
Harrington L, Blondon M, Cushman M, Kaunitz A, Allison M, Wang L, et al.
J Thromb Haemost . 2018 Mar; 16(5):886-892. PMID: 29504242
Summary: Background Vasomotor symptoms may be markers of changes in cardiovascular risk, but it is unknown whether these symptoms are associated with the risk of venous thrombosis (VT). Objective To...
7.
Seyerle A, Sitlani C, Noordam R, Gogarten S, Li J, Li X, et al.
Pharmacogenomics J . 2017 Jul; 18(2):215-226. PMID: 28719597
Thiazide diuretics, commonly used antihypertensives, may cause QT interval (QT) prolongation, a risk factor for highly fatal and difficult to predict ventricular arrhythmias. We examined whether common single-nucleotide polymorphisms (SNPs)...
8.
Roetker N, Armasu S, Pankow J, Lutsey P, Tang W, Rosenberg M, et al.
J Thromb Haemost . 2017 Apr; 15(7):1334-1343. PMID: 28445597
Summary: Background Taller height is associated with a greater risk of venous thromboembolism (VTE). Objectives To use instrumental variable (IV) techniques (Mendelian randomization) to further explore this relationship. Methods Participants...
9.
Floyd J, Sitlani C, Avery C, Noordam R, Li X, Smith A, et al.
Pharmacogenomics J . 2016 Dec; 18(1):127-135. PMID: 27958378
Sulfonylureas, a commonly used class of medication used to treat type 2 diabetes, have been associated with an increased risk of cardiovascular disease. Their effects on QT interval duration and...
10.
Harrington L, Marck B, Wiggins K, McKnight B, Heckbert S, Woods N, et al.
J Thromb Haemost . 2016 Nov; 15(1):80-90. PMID: 27797446
Summary: Background Oral use of exogenous estrogen/progestin alters hemostatic factor levels. The influence of endogenous hormones on these levels is incompletely characterized. Objectives Our study aimed to test whether, among...