S Przedborski
Overview
Explore the profile of S Przedborski including associated specialties, affiliations and a list of published articles.
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126
Citations
4877
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Recent Articles
1.
Chatila Z, Yadav A, Mares J, Flowers X, Yun T, Rashid M, et al.
bioRxiv
. 2023 Jun;
PMID: 37292857
All brain areas affected in Parkinson's disease (PD) show an abundance of microglia with an activated morphology together with increased expression of pro-inflammatory cytokines, suggesting that neuroinflammation may contribute to...
2.
Obeso J, Stamelou M, Goetz C, Poewe W, Lang A, Weintraub D, et al.
Mov Disord
. 2017 Sep;
32(9):1264-1310.
PMID: 28887905
This article reviews and summarizes 200 years of Parkinson's disease. It comprises a relevant history of Dr. James Parkinson's himself and what he described accurately and what he missed from...
3.
Lim L, Jackson-Lewis V, Wong L, Shui G, Goh A, Kesavapany S, et al.
Cell Death Differ
. 2011 Aug;
19(3):416-27.
PMID: 21818119
Parkinson's disease (PD) is a neurodegenerative disorder marked by the selective degeneration of dopaminergic neurons in the nigrostriatal pathway. Several lines of evidence indicate that mitochondrial dysfunction contributes to its...
4.
Przedborski S, Dawson T
Methods Mol Med
. 2011 Feb;
62:113-36.
PMID: 21318772
Neurodegenerative disorders are adult-onset disabling neurologic conditions such as Parkinson's disease (PD) in which specific subsets of brain neurons are dying. Without exception, the frequency of these disorders is increasing...
5.
Giladi N, Sutton M, Lo B, Przedborski S, Fahn S, Cadet J
Toxicol In Vitro
. 2010 Aug;
7(5):595-603.
PMID: 20732256
The highly selective cardiac-M(2) muscarinic acetylcholine receptor (mAChR) antagonist methoctramine shows a number of concentration-dependent biochemical responses. At micromolar concentrations it interacts allosterically with the mAChR and has 'agonist-like' effects...
6.
Schiffmann S, Mailleux P, Przedborski S, Halleux P, Lotstra F, Vanderhaeghen J
Neurochem Int
. 2010 May;
14(2):167-73.
PMID: 20504414
The distribution of cholecystokinin immunoreactive nerve cell bodies and processes is reported in the human striatum and adjacent structures such as the claustrum, the pallidum, the bed nucleus of the...
7.
De Laet M, Dassonville M, Steyaert H, Vanderveken E, Lotstra F, Vierendeels G, et al.
Neurochem Int
. 2010 May;
14(2):135-41.
PMID: 20504409
Ganglionic and aganglionic full-thickness samples, at 4 levels of the colon of 26 infants with Hirschsprung's disease, were studied by immunohistochemistry. In the distal part of the aganglionic bowel, we...
8.
Whittle A, Ross O, Naini A, Gordon P, Mistumoto H, Dachsel J, et al.
J Neural Transm (Vienna)
. 2006 Jul;
114(3):327-9.
PMID: 16865326
Pathogenic Lrrk2 Y1699C substitution observed in a large German-Canadian kindred presents a neurodegenerative disorder that is reminiscent of amyotrophic lateral sclerosis and Parkinsonism-Dementia Complex. We screened 54 patients with ALS...
9.
Gordon P, Doorish C, Montes J, Mosley R, Mosely R, Diamond B, et al.
Neurology
. 2006 Apr;
66(7):1117-9.
PMID: 16606934
The authors conducted a randomized controlled trial to test the safety and immunology of glatiramer acetate in ALS. Twenty treated patients were randomly assigned to daily or biweekly injections. Ten...
10.
Teismann P, Vila M, Choi D, Tieu K, Wu D, Jackson-Lewis V, et al.
Ann N Y Acad Sci
. 2003 Jul;
991:272-7.
PMID: 12846993
Parkinson's disease (PD) is a common neurodegenerative disorder characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta. Recent observations link cyclooxygenase type-2 (COX-2) to the...