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S P Hunt

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Articles 176
Citations 3285
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Recent Articles
1.
Porter A, Pillidge K, Tsai Y, Dudley J, Hunt S, Peirson S, et al.
Genes Brain Behav . 2015 Jan; 14(2):189-99. PMID: 25558794
Mice lacking functional neurokinin-1 receptors (NK1R-/-) display abnormal behaviours seen in Attention Deficit Hyperactivity Disorder (hyperactivity, impulsivity and inattentiveness). These abnormalities were evident when comparing the behaviour of separate (inbred:...
2.
Olango W, Geranton S, Roche M, Hunt S, Finn D
Eur J Pain . 2013 Jul; 18(2):182-91. PMID: 23873727
Background: Fear-conditioned analgesia (FCA) is the profound suppression of pain during exposure to conditioned aversive stimuli and is mediated at spinal and supraspinal levels. The endocannabinoid system plays a key...
3.
Weir R, Dudley J, Yan T, Grabowska E, Pena-Oliver Y, Ripley T, et al.
J Psychopharmacol . 2013 Jul; 28(3):270-81. PMID: 23845920
Genetically-altered mice, lacking functional NK1 receptors (NK1R-/-), express abnormal behaviours that are prominent in Attention Deficit Hyperactivity Disorder: namely, inattentiveness and impulsivity (indicated by their greater % omissions and premature...
4.
Roche M, Kerr D, Hunt S, Kelly J
Behav Brain Res . 2011 Dec; 228(1):91-8. PMID: 22155476
The substance P/NK1 receptor system plays an important role in the regulation of stress and emotional responding and as such had been implicated in the pathophysiology of anxiety and depression....
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Yan T, McQuillin A, Thapar A, Asherson P, Hunt S, Stanford S, et al.
J Psychopharmacol . 2009 Feb; 24(1):27-38. PMID: 19204064
Mice with functional genetic ablation of the Tacr1 (substance P-preferring receptor) gene (NK1R-/-) are hyperactive. Here, we investigated whether this is mimicked by NK1R antagonism and whether dopaminergic transmission is...
7.
Tebar L, Geranton S, Parsons-Perez C, Fisher A, Bayne R, Smith A, et al.
Proc Natl Acad Sci U S A . 2008 Aug; 105(32):11400-5. PMID: 18678917
A large number of cytokines and growth factors support the development and subsequent maintenance of postnatal motor neurons. RegIIIbeta, also known as Reg2 in rat and HIP/PAP1 in humans, is...
8.
Averill S, Inglis J, King V, Thompson S, Cafferty W, Shortland P, et al.
Neuroscience . 2008 Jul; 155(4):1227-36. PMID: 18652880
Reg-2 is a secreted protein that is expressed de novo in motoneurons, sympathetic neurons, and dorsal root ganglion (DRG) neurons after nerve injury and which can act as a Schwann...
9.
Livesey F, Hunt S
Curr Protoc Hum Genet . 2008 Apr; Chapter 11:Unit 11.5. PMID: 18428247
This unit outlines the polymerase chain reaction (PCR)-based technique of mRNA differential display, which identifies genes that are differentially expressed between cells or tissues. The basic protocol describes the actual...
10.
McCutcheon J, Fisher A, Guzdar E, Wood S, Lightman S, Hunt S
Eur J Neurosci . 2008 Feb; 27(3):683-90. PMID: 18279320
Genetic background affects animal phenotype and therefore is of particular relevance to studies using genetically manipulated mice. Strain differences in hypothalamic-pituitary-adrenocortical (HPA) axis activity may contribute to background-specificity of some...