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S Numa

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Articles 179
Citations 6485
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Recent Articles
1.
Numa S, Rodriguez L, Rodriguez D, Coy-Barrera E
Springerplus . 2015 Jul; 4:338. PMID: 26185740
One of the main pests of commercial rose crops in Colombia is the phytophagous mite Tetranychus urticae Koch. To manage this pest, synthetic chemicals have traditionally been used, some of...
2.
Tanabe T, Mikami A, Niidome T, Numa S, Adams B, Beam K
Ann N Y Acad Sci . 1993 Dec; 707:81-6. PMID: 9137544
No abstract available.
3.
Beam K, Adams B, Niidome T, Numa S, Tanabe T
Nature . 1992 Nov; 360(6400):169-71. PMID: 1331811
The skeletal muscle dihydropyridine (DHP) receptor serves dual functions, as a voltage sensor for excitation-contraction coupling and as an L-type calcium channel. Biochemical analysis indicates the presence of two forms...
4.
Heinemann S, Terlau H, Stuhmer W, Imoto K, Numa S
Nature . 1992 Apr; 356(6368):441-3. PMID: 1313551
The sodium channel, one of the family of structurally homologous voltage-gated ion channels, differs from other members, such as the calcium and the potassium channels, in its high selectivity for...
5.
Terlau H, Heinemann S, Stuhmer W, Pusch M, Conti F, Imoto K, et al.
FEBS Lett . 1991 Nov; 293(1-2):93-6. PMID: 1660007
The SS2 and adjacent regions of the 4 internal repeats of sodium channel II were subjected to single mutations involving, mainly, charged amino acid residues. These sodium channel mutants, expressed...
6.
Imoto K, Konno T, Nakai J, Wang F, Mishina M, Numa S
FEBS Lett . 1991 Sep; 289(2):193-200. PMID: 1717313
The channel pore of the nicotinic acetylcholine receptor (AChR) has been investigated by analysing single-channel conductances of systematically mutated Torpedo receptors expressed in Xenopus oocytes. The mutations mainly alter the...
7.
Tanabe T, Adams B, Numa S, Beam K
Nature . 1991 Aug; 352(6338):800-3. PMID: 1652692
Membrane depolarization causes many kinds of ion channels to open, a process termed activation. For both Na+ channels and Ca2+ channels, kinetic analysis of current has suggested that during activation...
8.
Konno T, Busch C, Von Kitzing E, Imoto K, Wang F, Nakai J, et al.
Proc Biol Sci . 1991 May; 244(1310):69-79. PMID: 1679551
To gain an insight into the molecular basis of the weak but significant selectivity among alkali metal cations of the nicotinic acetylcholine receptor (AChR) channel, we have determined single-channel conductance...
9.
Pusch M, Noda M, Stuhmer W, Numa S, Conti F
Eur Biophys J . 1991 Jan; 20(3):127-33. PMID: 1660394
1. Two mutants of the sodium channel II have been expressed in Xenopus oocytes and have been investigated using the patch-clamp technique. In mutant E387Q the glutamic acid at position...
10.
Higashida H, Hashii M, Fukuda K, Caulfield M, Numa S, Brown D
Proc Biol Sci . 1990 Oct; 242(1303):68-74. PMID: 1980742
Acetylcholine (ACh) can inhibit calcium currents (ICa) in nerve cells by activating muscarinic ACh receptors (mAChR). There are several different genetic subtypes of mAChR. It is not known which subtype(s)...