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S N Nazhat

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Articles 29
Citations 361
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Recent Articles
1.
Marelli B, Ghezzi C, Alessandrino A, Freddi G, Nazhat S
J Mater Chem B . 2020 Apr; 2(33):5339-5343. PMID: 32261754
Incorporation of anionic fibroin derived polypeptides into dense collagen gels provided a dynamic, three-dimensional, tissue-equivalent matrix together with biochemical cues that resembled the role of the bone morphogenic growth factors...
2.
Karunanayake G, Ng Y, Knowles J, Delgado A, Young A, Gulabivala K, et al.
J Mech Behav Biomed Mater . 2019 Jun; 97:330-338. PMID: 31153114
Objectives: To determine the effect of heat on flexural strength (FS), maximum strain (MS), storage modulus (SM), tan delta (TD) and chemical changes through micro-Raman spectroscopy of dentine exposed to...
3.
Simpson R, Nazhat S, Blaker J, Bismarck A, Hill R, Boccaccini A, et al.
J Mech Behav Biomed Mater . 2015 Jul; 50:277-89. PMID: 26164218
Bone substitute composite materials with poly(L-lactide-co-glycolide) (PLGA) matrices and four different bioactive fillers: CaCO3, hydroxyapatite (HA), 45S5 Bioglass(®) (45S5 BG), and ICIE4 bioactive glass (a lower sodium glass than 45S5...
4.
Addison W, Nelea V, Chicatun F, Chien Y, Tran-Khanh N, Buschmann M, et al.
Bone . 2014 Dec; 71:244-56. PMID: 25460184
Bone cell culture systems are essential tools for the study of the molecular mechanisms regulating extracellular matrix mineralization. MC3T3-E1 osteoblast cell cultures are the most commonly used in vitro model...
5.
Rosenzweig D, Chicatun F, Nazhat S, Quinn T
Acta Biomater . 2013 Jul; 9(12):9360-9. PMID: 23896567
Cell-based therapies such as autologous chondrocyte implantation require in vitro cell expansion. However, standard culture techniques require cell passaging, leading to dedifferentiation into a fibroblast-like cell type. Primary chondrocytes grown...
6.
Coyac B, Chicatun F, Hoac B, Nelea V, Chaussain C, Nazhat S, et al.
J Dent Res . 2013 May; 92(7):648-54. PMID: 23632809
While advances in biomineralization have been made in recent years, unanswered questions persist on bone- and tooth-cell differentiation, on outside-in signaling from the extracellular matrix, and on the link between...
7.
Mohammadi M, Ahmed I, Muja N, Almeida S, Rudd C, Bureau M, et al.
Acta Biomater . 2012 Jan; 8(4):1616-26. PMID: 22248526
Reinforcing biodegradable polymers with phosphate-based glass fibres (PGF) is of interest for bone repair and regeneration. In addition to increasing the mechanical properties, PGF can also release bioinorganics, as they...
8.
Blaker J, Nazhat S, Maquet V, Boccaccini A
Acta Biomater . 2010 Sep; 7(2):829-40. PMID: 20849987
The long-term (600days) in vitro degradation of highly porous poly(D,L-lactide) (PDLLA)/Bioglass-filled composite foams developed for bone tissue engineering scaffolds has been investigated in simulated body fluid (SBF). Foams of ∼93%...
9.
Dashti A, Ready D, Salih V, Knowles J, Barralet J, Wilson M, et al.
J Biomed Mater Res B Appl Biomater . 2010 Feb; 93(2):394-400. PMID: 20119947
Local delivery of antibiotics may provide the advantage of reducing the potential side effects associated with their systemic administration. This study assessed, in vitro, the antimicrobial efficacy of tetracycline hydrochloride...
10.
Buxton P, Bitar M, Gellynck K, Parkar M, BROWN R, Young A, et al.
Bone . 2008 May; 43(2):377-385. PMID: 18502716
Bone is distinguished from other tissues by its mechanical properties, in particular stiffness. However, we know little of how osteoblasts react to the stiffness of their microenvironment; in this study...