S Melethil
Overview
Explore the profile of S Melethil including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
120
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Recent Articles
1.
Smith S, Kraft S, Lewis D, Melethil S, Freeman L
J Vet Pharmacol Ther
. 2001 Feb;
23(6):339-44.
PMID: 11168910
The overall purpose of this study was to evaluate the pharmacodynamic response to warfarin in cats. The specific aim was to determine if a log-linear indirect response model (Nagashima et...
2.
Lovell M, Ehmann W, Markesbery W, Melethil S, Swyt C, Zatta P
J Toxicol Environ Health
. 1996 Aug;
48(6):637-48.
PMID: 8772803
A review of the literature of aluminum (Al) levels in biological samples, particularly Alzheimer's disease (AD) brain, reveals a lack of interlaboratory agreement at both the bulk and microprobe levels....
3.
Exley C, Burgess E, Day J, Jeffery E, Melethil S, Yokel R
J Toxicol Environ Health
. 1996 Aug;
48(6):569-84.
PMID: 8772799
In this study of the toxicokinetics of aluminum we have examined some of the fundamental issues that currently define our understanding of the toxicology of aluminum in humans. There is...
4.
Tang J, Melethil S
Pharm Res
. 1995 Jul;
12(7):1085-91.
PMID: 7494807
Purpose: The purpose of this investigation was to examine the effect of aging on the blood-brain barrier (BBB) transport of tryptophan. Methods: A well established in-situ brain perfusion technique was...
5.
6.
Shetty B, Badr M, Melethil S
J Pharm Sci
. 1994 Apr;
83(4):607-8.
PMID: 8046624
Hepatic metabolism of salicylic acid was studied using a single-pass liver perfusion technique. Livers obtained from male, Sprague-Dawley rats (200-300 g) were perfused with Krebs-Henseleit bicarbonate buffer containing the drug...
7.
Tang J, Xu Z, DOUGLAS F, Rakhit A, Melethil S
Life Sci
. 1993 Jan;
53(25):PL417-20.
PMID: 7902950
A previous communication from this laboratory reported that brain uptake of libenzapril, a small polar molecule, was enhanced in chronic hypertension (1). The objective of this investigation was to determine...
8.
Xu Z, Tang J, Xu Z, Melethil S
Toxicol Lett
. 1992 Oct;
63(1):7-12.
PMID: 1412525
Aluminum causes central nervous system (CNS) toxicities in both humans and various animal species. Although blood aluminum concentrations are monitored in the clinic, very little is known regarding the relationship...
9.
Peng J, Xu Z, Xu Z, PARKER Jr J, Friedlander E, Tang J, et al.
Mol Chem Neuropathol
. 1992 Aug;
17(1):79-89.
PMID: 1388451
In the present study the acute effect of intravenous aluminum chloride (1 mg/kg) on choline acetyltransferase (ChAT) and acetylcholinesterase (AChE) activities of rats was investigated. Aluminum was found to cross...
10.
Tang J, Rakhit A, DOUGLAS F, Melethil S
Pharm Res
. 1992 Feb;
9(2):236-43.
PMID: 1553348
Very little information is available on the permeability of the blood-brain barrier (BBB) to small polar drugs in chronic hypertension. The blood and cerebrospinal fluid (CSF) pharmacokinetics of libenzapril (LZP),...