S McClean
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Explore the profile of S McClean including associated specialties, affiliations and a list of published articles.
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53
Citations
389
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Recent Articles
1.
Lees-Murdock D, Khan D, Irwin R, Graham J, Hinch V, OHagan B, et al.
Br J Biomed Sci
. 2024 Mar;
81:12148.
PMID: 38501148
Active learning is a useful tool to enhance student engagement and support learning in diverse educational situations. We aimed to assess the efficacy of an active learning approach within a...
2.
Coulter-Parkhill A, Gault V, McClean S, Irwin N
Eur J Pharmacol
. 2023 Jun;
954:175855.
PMID: 37391009
Clinical approval of the glucagon-like peptide-1 (GLP-1) mimetic exenatide for the treatment of type 2 diabetes highlights the therapeutic effectiveness of venom-derived peptides. In the present study, we examined and...
3.
Coulter-Parkhill A, Dobbin S, Tanday N, Gault V, McClean S, Irwin N
Biochem Pharmacol
. 2023 Apr;
212:115544.
PMID: 37044298
Proof-of-concept for therapeutic application of venom-derived compounds in diabetes is exemplified by the incretin mimetic, exenatide, originally extracted from the saliva of the venomous Heloderma suspectum lizard. In this regard,...
4.
Schofield B, Rolfe U, McClean S, Hoskins R, Voss S, Benger J
BMC Emerg Med
. 2022 Jun;
22(1):95.
PMID: 35659572
Background: There are potential health gains such as reducing early deaths, years spent in ill-health and costs to society and the health and care system by encouraging NHS staff to...
5.
Schofield B, McClean S
Perspect Public Health
. 2021 Oct;
142(3):135-136.
PMID: 34674589
No abstract available.
6.
Omakobia E, McClean S, England J, Walden A
J Laryngol Otol
. 2021 May;
135(7):599-601.
PMID: 34016194
Objective: British Thyroid Association 2014 guidelines emphasised ultrasound assessment of nodules. One ultrasonographic differentiator of debatable relevance is intra-nodular vascularity. This is the first UK study conducted to address this...
7.
Craig S, Gault V, McClean S, Hamscher G, Irwin N
Mol Cell Endocrinol
. 2019 Jul;
496:110523.
PMID: 31352038
Xenin-25 undergoes rapid enzyme metabolism following secretion. Early studies demonstrated bioactivity of a C-terminal hexapeptide fragment of xenin-25, namely xenin-6, which were enhanced through introduction of a reduced N-terminal peptide...
8.
Pathak N, Pathak V, Gault V, McClean S, Irwin N, Flatt P
Biochem Pharmacol
. 2018 Jul;
155:264-274.
PMID: 30028989
Glucose-dependent insulinotropic hormone (GIP) and glucagon-like peptide-1 (GLP-1) are incretin hormones that exert an array of beneficial actions on metabolism and cognitive function. GLP-1-based therapeutics have been highly successful in...
9.
Kelly G, Kia A, Hassan F, OGrady S, Morgan M, Creaven B, et al.
Org Biomol Chem
. 2016 Oct;
14(39):9278-9286.
PMID: 27722734
Antimicrobial Peptides (AMPs) have unique anticancer properties, but their clinical application is currently limited by an inadequate margin of safety. A prodrug strategy associated with a combination therapy approach could...
10.
Condon L, McClean S
J Public Health (Oxf)
. 2016 Sep;
39(3):455-463.
PMID: 27591301
Background: There is evidence that key health behaviours of people who migrate deteriorate over time, which has a consequent impact upon the health of dependent children. As health in the...