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S M Offer

Explore the profile of S M Offer including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 113
Followers 0
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Recent Articles
1.
Nie Q, Shrestha S, Tapper E, Trogstad-Isaacson C, Bouchonville K, Lee A, et al.
Clin Pharmacol Ther . 2017 Mar; 102(4):662-670. PMID: 28295243
Dihydropyrimidine dehydrogenase (DPD; DPYD gene) variants have emerged as reliable predictors of adverse toxicity to the chemotherapy agent 5-fluorouracil (5-FU). The intronic DPYD variant rs75017182 has been recently suggested to...
2.
Elraiyah T, Jerde C, Shrestha S, Wu R, Nie Q, Giama N, et al.
Clin Pharmacol Ther . 2016 Oct; 101(3):382-390. PMID: 27727460
Clinical studies have identified specific genetic variants in dihydropyrimidine dehydrogenase (DPD; DPYD gene) as predictors of severe adverse toxicity to the commonly used chemotherapeutic 5-fluorouracil (5-FU); however, these studies have...
3.
Offer S, Diasio R
Clin Pharmacol Ther . 2013 Oct; 95(2):137. PMID: 24107927
No abstract available.
4.
Witzig T, Hu G, Offer S, Wellik L, Han J, Stenson M, et al.
Leukemia . 2013 Aug; 28(1):147-54. PMID: 23979523
Protein tyrosine phosphatases such as PTPN6 can be downregulated in various neoplasms. PTPN6 expression by immunohistochemistry in 40 diffuse large B-cell lymphoma (DLBCL) tumors was lost or suppressed in 53%...
5.
Offer S, Lee A, Mattison L, Fossum C, Wegner N, Diasio R
Clin Pharmacol Ther . 2013 Apr; 94(1):158-66. PMID: 23588312
5-Fluorouracil (5-FU) is used to treat many aggressive cancers, such as those of the colon, breast, and head and neck. The responses to 5-FU, with respect to both toxicity and...