S M MacKenzie
Overview
Explore the profile of S M MacKenzie including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
189
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Recent Articles
1.
Holloway C, MacKenzie S, Fraser R, Miller S, Barr M, Wilkinson D, et al.
Clin Endocrinol (Oxf)
. 2008 Aug;
70(3):363-71.
PMID: 18710464
Objective: Evidence suggests that high levels of aldosterone lead to hypertension and increased risk of cardiovascular disease. Around 15% of patients with essential hypertension have a raised aldosterone to renin...
2.
Smellie W, Hampton K, Bowley R, Bowlees R, Martin S, Shaw N, et al.
J Clin Pathol
. 2006 Dec;
60(7):740-8.
PMID: 17172476
This eighth best practice review examines four series of common primary care questions in laboratory medicine: (i) sodium abnormalities; (ii) faecal occult blood testing; (iii) warfarin management; and (iv) sputum...
3.
MacKenzie S, McLaughlin E, Perkins H, French N, Sutherland T, Jackson R, et al.
Biol Reprod
. 2005 Nov;
74(3):511-21.
PMID: 16306421
Recombinant myxoma viruses expressing rabbit zona pellucida 2 (rZP2) or rabbit zona pellucida 3 (rZP3) glycoproteins were constructed and tested in domestic rabbits to assess their potential to induce autoimmune...
4.
Ye P, Kenyon C, MacKenzie S, Jong A, Miller C, Gray G, et al.
Endocrinology
. 2005 Sep;
146(12):5287-93.
PMID: 16179417
Aldosterone synthase (CYP11B2) and 11beta-hydroxylase (CYP11B1) catalyze the production of aldosterone and corticosterone, respectively, in the rat adrenal cortex. Recently, there has been some debate as to whether these corticosteroids...
5.
MacKenzie S, Lai M, CLARK C, Fraser R, Gomez-Sanchez C, Seckl J, et al.
J Mol Endocrinol
. 2002 Dec;
29(3):319-25.
PMID: 12459034
The central nervous system produces many of the enzymes responsible for corticosteroid synthesis. A model system to study the regulation of this local system would be valuable. Previously, we have...
6.
MacKenzie S, HOWELLS A, Cox G, Ewart G
Genetica
. 2001 Apr;
108(3):239-52.
PMID: 11294610
The white, scarlet, and brown genes of Drosophila melanogaster encode ABC transporters involved with the uptake and storage of metabolic precursors to the red and brown eye colour pigments. It...
7.
Lo Y, MacKenzie S, Howie A, Apps D, Mason J, Williams B, et al.
Endocr Res
. 2001 Feb;
26(4):737-45.
PMID: 11196450
Immunohistochemistry using a StAR peptide antiserum had previously revealed strong staining in rat and bovine adrenal medulla, suggesting the presence of a protein immunogenically related to StAR. Western blots of...
8.
MacKenzie S, CLARK C, Ingram M, Lai M, Seckl J, Gomez-Sanchez C, et al.
Endocr Res
. 2001 Feb;
26(4):531-5.
PMID: 11196425
11beta-hydroxylase and aldosterone synthase catalyse the final stages of corticosterone and aldosterone synthesis respectively. Previously, we established that they are expressed in the rat brain, particularly the cerebellum and the...
9.
MacKenzie S, CLARK C, Fraser R, Gomez-Sanchez C, Connell J, Davies E
J Mol Endocrinol
. 2000 Jun;
24(3):321-8.
PMID: 10828825
The terminal stages of cortisol and aldosterone production in the human adrenal gland are catalysed by the enzymes 11beta-hydroxylase and aldosterone synthase, which are encoded by the CYP11B1 and CYP11B2...
10.
MacKenzie S, Brooker M, Gill T, Cox G, HOWELLS A, Ewart G
Biochim Biophys Acta
. 1999 Jul;
1419(2):173-85.
PMID: 10407069
The white, brown and scarlet genes of Drosophila melanogaster encode proteins which transport guanine or tryptophan (precursors of the red and brown eye colour pigments) and belong to the ABC...