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S M Lemon

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Articles 150
Citations 3733
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Recent Articles
1.
McGivern D, Lemon S
Oncogene . 2011 Jan; 30(17):1969-83. PMID: 21258404
The development of hepatocellular carcinoma (HCC) in persons who are persistently infected with hepatitis C virus (HCV) is a growing problem worldwide. Current antiviral therapies are not effective in many...
2.
Wang T, Campbell R, Yi M, Lemon S, Weinman S
J Viral Hepat . 2009 Dec; 17(11):784-93. PMID: 20002299
Hepatitis C virus (HCV) infection results in several changes in mitochondrial function including increased reactive oxygen species (ROS) production and greater sensitivity to oxidant, Ca(2+) and cytokine-induced cell death. Prior...
3.
Fox J, Feng Y, Theve E, Raczynski A, Fiala J, Doernte A, et al.
Gut . 2009 Oct; 59(1):88-97. PMID: 19850960
Background And Aims: Hepatocellular carcinoma (HCC) frequently results from synergism between chemical and infectious liver carcinogens. Worldwide, the highest incidence of HCC is in regions endemic for the foodborne contaminant...
4.
Locarnini S, Shaw T, Dean J, Colledge D, Thompson A, Li K, et al.
J Clin Virol . 2005 Jan; 32(2):113-21. PMID: 15653413
Background: The expression of the hepatitis Be antigen (HBeAg) is one of several strategies used by hepatitis B virus (HBV) to ensure persistence. The HBeAg may function as a toleragen...
5.
Lau D, Ma H, Lemon S, Doo E, Ghany M, Miskovsky E, et al.
J Viral Hepat . 2003 Jun; 10(4):331-4. PMID: 12823602
Simple, rapid and accurate assays for hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) are helpful for clinical diagnosis and field epidemiological surveys. A commercially developed, rapid...
6.
Sun J, Bodola F, Fan X, Irshad H, Soong L, Lemon S, et al.
J Virol . 2001 Nov; 75(24):11992-8. PMID: 11711589
Several hepatitis C virus (HCV) proteins have been shown in vitro to interact with host cellular components that are involved in immune regulation. However, there is a paucity of data...
7.
Rijnbrand R, Bredenbeek P, Haasnoot P, Kieft J, Spaan W, Lemon S
RNA . 2001 May; 7(4):585-97. PMID: 11345437
Some studies suggest that the hepatitis C virus (HCV) internal ribosome entry site (IRES) requires downstream 5' viral polyprotein-coding sequence for efficient initiation of translation, but the role of this...
8.
Dollenmaier G, Mosier S, Scholle F, Sharma N, McKnight K, Lemon S
Virology . 2001 Mar; 281(2):216-30. PMID: 11277694
Human rhinovirus (HRV) replicons have the potential to serve as respiratory vaccine vectors for mucosal immunization in humans. However, since many vaccine immunogens of interest are glycosylated, an important concern...
9.
Kunkel M, Lorinczi M, Rijnbrand R, Lemon S, Watowich S
J Virol . 2001 Feb; 75(5):2119-29. PMID: 11160716
Little is known about the assembly pathway and structure of hepatitis C virus (HCV) since insufficient quantities of purified virus are available for detailed biophysical and structural studies. Here, we...
10.
Butkiewicz N, Yao N, Zhong W, Ingravallo P, Zhang R, Durkin J, et al.
J Virol . 2001 Feb; 74(9):4291-301. PMID: 10756044
GB virus B (GBV-B) is closely related to hepatitis C virus (HCV) and causes acute hepatitis in tamarins (Saguinus species), making it an attractive surrogate virus for in vivo testing...