S M Crain
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Explore the profile of S M Crain including associated specialties, affiliations and a list of published articles.
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141
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1262
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Recent Articles
11.
Crain S, Shen K
Brain Res
. 1996 Nov;
741(1-2):275-83.
PMID: 9001733
The ultra-potent opioid analgesic, etorphine, elicits naloxone-reversible, dose-dependent inhibitory effects, i.e., shortening of the action potential duration (APD) of naive and chronic morphine-treated sensory dorsal root ganglion (DRG) neurons, even...
12.
Crain S, Shen K
Neurochem Res
. 1996 Nov;
21(11):1347-51.
PMID: 8947924
Electrophysiologic studies of opioid effects on nociceptive types of dorsal root ganglion (DRG) neurons in organotypic cultures have shown that morphine and most mu, delta, and kappa opioid agonists can...
13.
Shen K, Crain S
Brain Res
. 1995 Dec;
701(1-2):158-66.
PMID: 8925279
The mechanism of action of the dimeric enkephalin peptide, biphalin (Tyr-D-Ala-Gly-Phe-NH2)2, which was previously shown to have remarkable high antinociceptive potency and low dependence liability in vivo, has now been...
14.
Crain S, Shen K
Proc Natl Acad Sci U S A
. 1995 Nov;
92(23):10540-4.
PMID: 7479836
Ultra-low picomolar concentrations of the opioid antagonists naloxone (NLX) and naltrexone (NTX) have remarkably potent antagonist actions on excitatory opioid receptor functions in mouse dorsal root ganglion (DRG) neurons, whereas...
15.
Wu G, Fan S, Lu Z, Ledeen R, Crain S
J Neurosci Res
. 1995 Nov;
42(4):493-503.
PMID: 8568936
Prolongation of the action potential duration of dorsal root ganglion (DRG) neurons by low (nM) concentrations of opioids occurs through activation of excitatory opioid receptors that are positively coupled via...
16.
Fan S, Crain S
Brain Res
. 1995 Oct;
696(1-2):97-105.
PMID: 8574691
The effects of the mu opioid receptor agonists, morphine and Tyr-D-Ala-Gly-N-methyl-Phe-Gly-ol (DAGO), the delta opioid receptor agonist, Tyr-D-Pen-Gly-Phe-D-penicillamine (DPDPE) and the kappa-opioid receptor agonist, dynorphin A-(1-13) on the whole-cell K+...
17.
Crain S, Shen K
Brain Res
. 1995 Oct;
694(1-2):103-10.
PMID: 8974633
Chronic morphine-treated dorsal-root ganglion (DRG) neurons in DRG/spinal cord explant cultures were previously shown to become supersensitive to the excitatory effects of remarkably low concentrations of the opioid agonists, morphine...
18.
Shen K, Crain S
Brain Res
. 1995 Feb;
673(1):30-8.
PMID: 7757476
We recently showed that the opioid alkaloids, etorphine, dihydroetorphine and diprenorphine, have remarkably potent antagonist actions on excitatory opioid receptor functions in mouse sensory dorsal root ganglion (DRG) neurons. Pretreatment...
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