S L Patrick
Overview
Explore the profile of S L Patrick including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
323
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Recent Articles
1.
Evidence for a role of endogenous cannabinoids in the modulation of acute and tonic pain sensitivity
Strangman N, Patrick S, Hohmann A, TSOU K, Walker J
Brain Res
. 1998 Dec;
813(2):323-8.
PMID: 9838180
The competitive CB1 receptor antagonist SR141716A was used to test the hypothesis that endogenous cannabinoids modulate tonic pain sensitivity. Pretreatment with the antagonist significantly enhanced the response to a chemical...
2.
Patrick S, Khen S, Patrick R, TSOU K, Walker J
Neurosci Lett
. 1998 Jul;
248(3):171-4.
PMID: 9654336
Cannabinoid receptors in the brain are highly concentrated in the basal ganglia, which is in accordance with their well known effects on motor behavior. In this study, rats with 6-hydroxydopamine...
3.
Patrick S, Kadohiro J, WAXMAN S, Curb J, Orchard T, Dorman J, et al.
Diabetes Care
. 1997 Jun;
20(6):983-7.
PMID: 9167110
Objective: The Hawaii IDDM Registry was created to determine the incidence rate of IDDM among children aged < 15 years of Oahu between 1980 and 1990. Because of the multiracial...
4.
Matsumoto R, Bowen W, Walker J, Patrick S, Zambon A, Vo V, et al.
Eur J Pharmacol
. 1996 Apr;
301(1-3):31-40.
PMID: 8773444
Radioligand binding and behavioral studies were conducted to determine whether a relationship existed between the motor effects produced by (+)-pentazocine and its binding to sigma sites. Scatchard analyses revealed decreased...
5.
Patrick S, Patrick R, Walker J
Neurosci Lett
. 1996 Mar;
206(1):21-4.
PMID: 8848272
The effect of unilateral intranigral cannabinoid receptor stimulation on rotational behavior was explored. The potent cannabinoid agonist CP 55,940 (5 and 10 micrograms/0.5 microliter) induced contralateral turning when microinjected unilaterally...
6.
TSOU K, Patrick S, Walker J
Eur J Pharmacol
. 1995 Jul;
280(3):R13-5.
PMID: 8566091
Tolerance to delta 9-tetrahydrocannabinol (delta 9-THC) was produced in rats by twice daily injections (15 mg/kg i.p.) for 6.5 days. Administration of the cannabinoid antagonist SR141716A (i.p. or i.c.v.) induced...
7.
Weiser S, Patrick S, Mascarella S, Bai X, Carroll F, Walker J, et al.
Eur J Pharmacol
. 1995 Feb;
275(1):1-7.
PMID: 7774655
The effects of sigma ligands on turning behavior and striatal tyrosine hydroxylase activity were determined following microinjection of two chemically dissimilar sigma ligands into the rat substantia nigra. Striatal tyrosine...
8.
Martin W, Patrick S, Coffin P, TSOU K, Walker J
Life Sci
. 1995 Jan;
56(23-24):2103-9.
PMID: 7776838
Microinjections of low doses of the potent and selective cannabinoids WIN 55,212-2 and CP 55,940 into the lateral ventricle produce long-lasting reduction in sensitivity to noxious thermal stimuli (1). To...
9.
Leitner M, Hohmann A, Patrick S, Walker J
Eur J Pharmacol
. 1994 Jun;
259(1):65-9.
PMID: 7957595
In vitro binding experiments were performed to determine whether known subtypes of the putative sigma receptor exhibit a differential distribution across brain regions and species. Rat brains were dissected into...
10.
Martin W, Lai N, Patrick S, TSOU K, Walker J
Brain Res
. 1993 Dec;
629(2):300-4.
PMID: 8111633
Intraventricular administration of 5 or 20 micrograms of the cannabinoids WIN55,212-2 and CP-55,940 markedly reduced rat's responses to noxious thermal stimuli in the tail-flick test; no significant effect was found...