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S L Free

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Articles 42
Citations 720
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Recent Articles
1.
Eriksson S, Free S, Thom M, Symms M, Martinian L, Duncan J, et al.
J Neurosci Methods . 2009 May; 181(1):111-8. PMID: 19433106
Voxel-based morphometry (VBM) is commonly used to study systematic differences in brain morphology from patients with various disorders, usually by comparisons with control subjects. It has often been suggested, however,...
2.
Bartlett P, Symms M, Free S, Duncan J
AJNR Am J Neuroradiol . 2007 Jun; 28(6):1095-8. PMID: 17569966
Background And Purpose: T2 mapping is useful for identifying and quantifying abnormalities of the hippocampus and amygdala. It is particularly useful in the presurgical evaluation of patients with temporal lobe...
3.
Eriksson S, Free S, Thom M, Martinian L, Symms M, Salmenpera T, et al.
Neuroimage . 2007 Jun; 37(1):48-55. PMID: 17555988
Newer MRI methods can detect cerebral abnormalities not identified on routine imaging in patients with focal epilepsy. Correlation of MRI with histopathology is necessary to understand the basis of MRI...
4.
Eriksson S, Free S, Thom M, Martinian L, Sisodiya S
Neuropathol Appl Neurobiol . 2006 Apr; 32(3):260-70. PMID: 16640644
White matter neuronal density has been correlated with clinical outcome after temporal lobectomy for refractory epilepsy. Both morphometric 2D (two-dimensional) and stereological 3D (three-dimensional) analyses of neuronal density have been...
5.
Thompson P, Mitchell T, Free S, Williamson K, Hanson I, Van Heyningen V, et al.
Neurology . 2004 Apr; 62(7):1216-8. PMID: 15079031
Fourteen patients with PAX6 gene mutations and previously identified MRI abnormalities were administered tests of cognitive functioning. No deficits were found. A subgroup with agenesis of the anterior commissure performed...
6.
Bamiou D, Musiek F, Sisodiya S, Free S, Mitchell T, Davies R
Neurology . 2004 Feb; 62(3):489-90. PMID: 14872040
Heterozygous PAX6 mutation is associated with an absent or hypoplastic anterior commissure and a reduction in the area of the corpus callosum. The authors found deficient auditory interhemispheric transfer in...
7.
Merschhemke M, Mitchell T, Free S, Hammers A, Kinton L, Siddiqui A, et al.
Neuroimage . 2003 Apr; 18(3):642-9. PMID: 12667841
Malformations of cortical development (MCD) are a common etiology for epilepsy. Laminar heterotopia, bilateral subependymal heterotopia, and lissencephaly have a genetic basis. No gene mutations have yet been identified in...
8.
Hagemann G, Lemieux L, Free S, Krakow K, Everitt A, Kendall B, et al.
J Neurol . 2003 Jan; 249(12):1651-8. PMID: 12529786
Cerebellar atrophy is assumed to be a common finding in patients suffering from epilepsy. Anticonvulsants as well as seizure activity itself have been considered to be responsible for it but...
9.
Thom M, Sisodiya S, Lin W, Mitchell T, Free S, Stevens J, et al.
Neurology . 2002 Jun; 58(11):1683-6. PMID: 12058101
Hippocampal malformations in patients with epilepsy usually are reported in the context of widespread cortical malformations. Isolated hippocampal malformations are more rarely identified in MRI studies with little documentation of...
10.
Mitchell T, Stevens J, Free S, Sander J, Shorvon S, Sisodiya S
Neurology . 2002 Apr; 58(8):1297-9. PMID: 11971106
The authors report a novel human brain malformation characterized by the absence of the anterior commissure without callosal agenesis, but associated with gross unilateral panhemispheric malformation incorporating subependymal heterotopia, subcortical...