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S L Christian

Explore the profile of S L Christian including associated specialties, affiliations and a list of published articles. Areas
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Articles 38
Citations 851
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Recent Articles
1.
Pongnopparat T, Tingley G, Gao Y, Brosnan J, Brosnan M, Christian S
Amino Acids . 2021 Sep; 53(10):1589-1595. PMID: 34550462
One-carbon units, critical intermediates for cell growth, may be produced by a variety of means, one of which is via the production of formate. Excessive formate accumulation, known as formate...
2.
Komatsu Y, Hirasawa K, Christian S
Genom Data . 2015 Oct; 4:84-7. PMID: 26484185
Oncolytic viruses exploit alterations in cancer cells to specifically infect cancer cells but not normal healthy cells. Previous work has shown that oncogenic Ras interferes with interferon (IFN) signaling to...
3.
Komatsu Y, Christian S, Ho N, Pongnopparat T, Licursi M, Hirasawa K
Oncogene . 2014 Oct; 34(30):3985-93. PMID: 25347735
Oncolytic viruses exploit common molecular changes in cancer cells, which are not present in normal cells, to target and kill cancer cells. Ras transformation and defects in type I interferon...
4.
Sullivan C, Christian S, Shieh J, Metry D, Blei F, Krol A, et al.
Mol Syndromol . 2013 May; 4(3):114-8. PMID: 23653582
Segmental hemangiomas of the head and neck can be associated with multiple congenital anomalies in the disorder known as PHACE syndrome (OMIM 606519) (posterior fossa malformations, hemangioma, arterial anomalies, cardiac...
5.
Licursi M, Christian S, Pongnopparat T, Hirasawa K
Gene Ther . 2011 Mar; 18(6):631-6. PMID: 21368899
Bicistronic vectors are essential to achieve efficient expression of multiple genes in gene therapy protocols and biomedical applications. Internal ribosome entry site (IRES) elements have been utilized to initiate expression...
6.
Zhang D, Cheng L, Qian Y, Alliey-Rodriguez N, Kelsoe J, Greenwood T, et al.
Mol Psychiatry . 2008 Dec; 14(4):376-80. PMID: 19114987
An overall burden of rare structural genomic variants has not been reported in bipolar disorder (BD), although there have been reports of cases with microduplication and microdeletion. Here, we present...
7.
Roohi J, Montagna C, Tegay D, Palmer L, DeVincent C, Pomeroy J, et al.
J Med Genet . 2008 Mar; 46(3):176-82. PMID: 18349135
Background: Autism spectrum disorder (ASD) is a developmental disorder of the central nervous system of largely unknown aetiology. The prevalence of the syndrome underscores the need for biological markers and...
8.
Maheshwari M, Christian S, Liu C, Badner J, Detera-Wadleigh S, Gershon E, et al.
BMC Genomics . 2002 Oct; 3(1):30. PMID: 12392603
Background: Multiple candidate regions as sites for Schizophrenia and Bipolar susceptibility genes have been reported, suggesting heterogeneity of susceptibility genes or oligogenic inheritance. Linkage analysis has suggested chromosome 13q32 as...
9.
Fantes J, Mewborn S, Lese C, Hedrick J, Brown R, Dyomin V, et al.
J Med Genet . 2002 Mar; 39(3):170-7. PMID: 11897815
Clinical cytogenetic laboratories frequently identify an apparent duplication of proximal 15q that does not involve probes within the PWS/AS critical region and is not associated with any consistent phenotype. Previous...
10.
Liu C, Badner J, Christian S, Guroff J, Detera-Wadleigh S, Gershon E
Am J Med Genet . 2001 May; 105(4):375-80. PMID: 11378853
A region between D13S71 and D13S274 on 13q32 showed linkage to bipolar disorder (BP) based on a genome scan using markers with an average spacing of approximately 6 cM and...