S J Meachem
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Explore the profile of S J Meachem including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
377
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Recent Articles
1.
McCabe M, Tarulli G, Laven-Law G, Matthiesson K, Meachem S, McLachlan R, et al.
Hum Reprod
. 2016 Feb;
31(4):875-86.
PMID: 26908839
Study Question: Are Sertoli cell tight junctions (TJs) disrupted in men undergoing hormonal contraception? Summary Answer: Localization of the key Sertoli cell TJ protein, claudin-11, was markedly disrupted by 8...
2.
Notini A, McClive P, Meachem S, van den Bergen J, Western P, Gustin S, et al.
Sex Dev
. 2012 Jul;
6(5):223-30.
PMID: 22797524
In an effort to identify novel candidate genes involved in testis determination, we previously used suppression subtraction hybridisation PCR on male and female whole embryonic (12.0-12.5 days post coitum) mouse...
3.
Identification of specific sites of hormonal regulation in spermatogenesis in rats, monkeys, and man
McLachlan R, ODonnell L, Meachem S, Stanton P, de Kretser D, Pratis K, et al.
Recent Prog Horm Res
. 2002 May;
57:149-79.
PMID: 12017541
A detailed understanding of the hormonal regulation of spermatogenesis is required for the informed assessment and management of male fertility and, conversely, for the development of safe and reversible male...
4.
Meachem S, Nieschlag E, Simoni M
Eur J Endocrinol
. 2001 Nov;
145(5):561-71.
PMID: 11720872
The recent availability of specific inhibin assays has demonstrated that inhibin B is the relevant circulating inhibin form in the human male. Inhibin B is a dimer of an alpha...
5.
Meachem S, McLachlan R, Stanton P, Robertson D, Wreford N
J Androl
. 1999 Dec;
20(6):756-62; discussion 755.
PMID: 10591615
Follicle-stimulating hormone (FSH) plays an important part in testicular development. Its role in the regulation of spermatogenesis in the adult, however, remains controversial. This study aimed to explore the role...
6.
Robertson K, ODonnell L, Jones M, Meachem S, Boon W, Fisher C, et al.
Proc Natl Acad Sci U S A
. 1999 Jul;
96(14):7986-91.
PMID: 10393934
It is well established that spermatogenesis is controlled by gonadotrophins and testosterone. However, a role for estrogens in male reproduction recently was suggested in adult mice deficient in estrogen receptor...
7.
Meachem S, Wreford N, Stanton P, Robertson D, McLachlan R
J Androl
. 1999 Jan;
19(6):725-35.
PMID: 9876024
The role of follicle-stimulating hormone (FSH) in adult rat spermatogenesis is unclear. Although exogenous testosterone (T) restores spermatogenesis following gonadotropin-releasing hormone (GnRH) immunization or T plus estradiol (TE) treatments, an...
8.
Duckett R, Wreford N, Meachem S, McLachlan R, Hedger M
J Androl
. 1998 Feb;
18(6):656-62.
PMID: 9432138
The objective of this study was to investigate the role of androgens and nonandrogenic Leydig cell products in maintaining Leydig cell and macrophage numbers in the testis of the adult...
9.
Meachem S, Wreford N, Robertson D, McLachlan R
Int J Androl
. 1997 Apr;
20(2):70-9.
PMID: 9292316
Spermatogonial proliferation is a critical but poorly understood determinant of the spermatogenic process. In rats, exogenous testosterone plus oestradiol (TE) markedly suppresses serum LH and testicular testosterone levels. In the...
10.
Meachem S, McLachlan R, de Kretser D, Robertson D, Wreford N
Biol Reprod
. 1996 Jan;
54(1):36-44.
PMID: 8837998
It is believed that Sertoli cells support a finite number of germ cells and that Sertoli cell number may help determine the spermatogenic capacity of the adult. In the rat,...