S I K Semple
Overview
Explore the profile of S I K Semple including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
107
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Recent Articles
1.
Papanastasiou G, Williams M, Dweck M, Mirsadraee S, Weir N, Fletcher A, et al.
IEEE Trans Radiat Plasma Med Sci
. 2018 Jul;
2(3):259-271.
PMID: 30003181
Kinetic modelling of myocardial perfusion imaging data allows the absolute quantification of myocardial blood flow (MBF) and can improve the diagnosis and clinical assessment of coronary artery disease (CAD). Positron...
2.
Eddowes P, McDonald N, Davies N, Semple S, Kendall T, Hodson J, et al.
Aliment Pharmacol Ther
. 2017 Dec;
47(5):631-644.
PMID: 29271504
Background: Validated diagnostic tools that are accurate, cost effective and acceptable to patients are required for disease stratification and monitoring in NAFLD. Aims: To investigate the performance and cost of...
3.
Denison F, MacNaught G, Semple S, Terris G, Walker J, Anblagan D, et al.
AJNR Am J Neuroradiol
. 2017 Mar;
38(5):1037-1044.
PMID: 28302607
Background And Purpose: Offspring exposed to maternal diabetes are at increased risk of neurocognitive impairment, but its origins are unknown. With MR imaging, we investigated the feasibility of comprehensive assessment...
4.
Di Giovanni P, Ahearn T, Semple S, Lovell L, Miller I, Gilbert F, et al.
Breast Cancer Res Treat
. 2012 Mar;
133(3):1199-206.
PMID: 22447179
Breast cancers are evolving, multi-scale systems that are characterized by varied complex spatial structures. In this study, we measured the structural characteristics of 33 breast tumours in patients who were...
5.
Fassler S, Fernandes P, Semple S, Brierley A
J Fish Biol
. 2010 Aug;
74(1):296-303.
PMID: 20735542
Changes in swimbladder morphology in an Atlantic herring Clupea harengus with pressure were examined by magnetic resonance imaging of a dead fish in a purpose-built pressure chamber. Swimbladder volume changed...
6.
Egred M, Waiter G, Al-Mohammad A, Semple S, Redpath T, Walton S
Eur J Intern Med
. 2006 Dec;
17(8):551-5.
PMID: 17142173
Background: Blood oxygen level dependent (BOLD) T2* MRI detects signal variance within the myocardium based on changes in the deoxyhaemoglobin level following pharmacological stress, and it has the potential to...
7.
Egred M, Waiter G, Semple S, Redpath T, Al-Mohammad A, Norton M, et al.
Int J Cardiol
. 2006 Jul;
115(1):36-41.
PMID: 16824632
Background: Blood oxygen level-dependent (BOLD) MRI relies on changes in deoxyhaemoglobin level in tissues under stress for signal variation and may be used for detection of ischaemic myocardium. Methods: 15...
8.
Semple S, Staff R, Heys S, Redpath T, Welch A, Ahearn T, et al.
Ann Oncol
. 2006 Jun;
17(9):1393-8.
PMID: 16788001
Background: The aim of the study was to investigate whether pre-therapy vascular delivery assessment [using dynamic contrast enhanced magnetic resonance imaging (DCE-MRI)] can predict reduction in breast cancer metabolism [detected...
9.
Ahearn T, Staff R, Redpath T, Semple S
Phys Med Biol
. 2005 Apr;
50(9):N85-92.
PMID: 15843726
The use of curve-fitting and compartmental modelling for calculating physiological parameters from measured data has increased in popularity in recent years. Finding the 'best fit' of a model to data...
10.
Ahearn T, Staff R, Redpath T, Semple S
Phys Med Biol
. 2004 Jun;
49(10):2041-51.
PMID: 15214540
Dynamic contrast enhanced MRI (DCE-MRI) and pharmacokinetic models have been used to measure tumour permeability (K(trans)) and leakage volume (ve) in numerous studies. The construction of pharmacokinetic models describing such...