S Hossein Fatemi
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Explore the profile of S Hossein Fatemi including associated specialties, affiliations and a list of published articles.
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Articles
68
Citations
3996
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Recent Articles
1.
Fatemi S, Eschenlauer A, Aman J, Folsom T, Chekouo T
Cereb Cortex
. 2024 May;
34(13):161-171.
PMID: 38696595
Autism spectrum disorder (ASD) is a developmental disorder with a rising prevalence and unknown etiology presenting with deficits in cognition and abnormal behavior. We hypothesized that the investigation of the...
2.
Fatemi S, Otte E, Folsom T, Eschenlauer A, Roper R, Aman J, et al.
Genes (Basel)
. 2024 Apr;
15(4).
PMID: 38674386
Down syndrome (DS) is the most common form of inherited intellectual disability caused by trisomy of chromosome 21, presenting with intellectual impairment, craniofacial abnormalities, cardiac defects, and gastrointestinal disorders. The...
3.
Folsom T, Higgins L, Markowski T, Griffin T, Fatemi S
Synapse
. 2018 Sep;
73(1):e22069.
PMID: 30176067
The fragile X mental retardation 1 knockout (Fmr1 KO) mouse replicates behavioral deficits associated with autism, fragile X syndrome, and schizophrenia. Less is known whether protein expression changes are consistent...
4.
Fatemi S, Wong D, Brasic J, Kuwabara H, Mathur A, Folsom T, et al.
Cerebellum Ataxias
. 2018 Feb;
5:3.
PMID: 29449954
Background: Autism is a neurodevelopmental disorder that is first manifested during early childhood. Postmortem experiments have identified significantly elevated expression of metabotropic glutamate receptor 5 (mGluR5) in cerebellar vermis and...
5.
Fatemi S, Folsom T, Thuras P
Neuroreport
. 2017 Sep;
28(16):1066-1070.
PMID: 28902714
Schizophrenia is a severe, debilitating, neurodevelopmental disorder that affects 1% of the world's population. Recent findings from our laboratory have identified reduced levels of fragile X mental retardation protein (FMRP)...
6.
Fatemi S, Folsom T, Thuras P
Synapse
. 2017 Mar;
71(7).
PMID: 28316115
Schizophrenia and bipolar disorder are complex psychiatric disorders that affect millions of people worldwide. Evidence from gene association and postmortem studies has identified abnormalities of the gamma-aminobutyric acid (GABA) signaling...
7.
Fatemi S, Folsom T, Liesch S, Kneeland R, Karkhane Yousefi M, Thuras P
J Neurosci Res
. 2016 Oct;
95(5):1110-1122.
PMID: 27735078
Prenatal viral infection has been identified as a potential risk factor for the development of neurodevelopmental disorders such as schizophrenia and autism. Additionally, dysfunction in gamma-aminobutyric acid, Reelin, and fragile...
8.
Frye R, Casanova M, Fatemi S, Folsom T, Reutiman T, Brown G, et al.
Front Neurosci
. 2016 Jun;
10:192.
PMID: 27242398
This manuscript reviews biological abnormalities shared by autism spectrum disorder (ASD) and epilepsy. Two neuropathological findings are shared by ASD and epilepsy: abnormalities in minicolumn architecture and γ-aminobutyric acid (GABA)...
9.
Folsom T, Thuras P, Fatemi S
Schizophr Res
. 2015 May;
165(2-3):201-11.
PMID: 25956630
Fragile X mental retardation protein (FMRP) is an RNA binding protein with 842 target mRNAs in mammalian brain. Silencing of the fragile X mental retardation 1 (FMR1) gene leads to...
10.
Fatemi S, Folsom T
Schizophr Res
. 2014 Nov;
167(1-3):42-56.
PMID: 25432637
Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain. GABAergic receptor abnormalities have been documented in several major psychiatric disorders including schizophrenia, mood disorders, and autism. Abnormal expression...