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S Helmling

Explore the profile of S Helmling including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 210
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Recent Articles
1.
Kobelt P, Helmling S, Stengel A, Wlotzka B, Andresen V, Klapp B, et al.
Gut . 2005 Jul; 55(6):788-92. PMID: 15994217
Background And Aims: Ghrelin, the natural ligand of the growth hormone secretagogue receptor 1a, is the most powerful peripherally active orexigenic agent known. In rodents, ghrelin administration stimulates growth hormone...
2.
Helmling S, Moyroud E, Schroeder W, Roehl I, Kleinjung F, Stark S, et al.
Nucleosides Nucleotides Nucleic Acids . 2003 Oct; 22(5-8):1035-8. PMID: 14565337
Synthesis of 2'-fluoro-nucleosides from L-arabinose in order to perform the synthesis of 2'-fluoro-Spiegelmers binding to a neuropeptide.
3.
Helmling S, Zhelkovsky A, Moore C
Mol Cell Biol . 2001 Mar; 21(6):2026-37. PMID: 11238938
Fip1 is an essential component of the Saccharomyces cerevisiae polyadenylation machinery and the only protein known to interact directly with poly(A) polymerase (Pap1). Its association with Pap1 inhibits the extension...
4.
Bard J, Zhelkovsky A, Helmling S, Earnest T, Moore C, Bohm A
Science . 2000 Aug; 289(5483):1346-9. PMID: 10958780
Polyadenylate [poly(A)] polymerase (PAP) catalyzes the addition of a polyadenosine tail to almost all eukaryotic messenger RNAs (mRNAs). The crystal structure of the PAP from Saccharomyces cerevisiae (Pap1) has been...
5.
Zhao J, Kessler M, Helmling S, OConnor J, Moore C
Mol Cell Biol . 1999 Oct; 19(11):7733-40. PMID: 10523662
CF II, a factor required for cleavage of the 3' ends of mRNA precursor in Saccharomyces cerevisiae, has been shown to contain four polypeptides. The three largest subunits, Cft1/Yhh1, Cft2/Ydh1,...
6.
Zhelkovsky A, Helmling S, Moore C
Mol Cell Biol . 1998 Sep; 18(10):5942-51. PMID: 9742111
The interaction of the Fip1 subunit of polyadenylation factor I with the Saccharomyces cerevisiae poly(A) polymerase (PAP) was assayed in vivo by two-hybrid analysis and was found to involve two...