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S H Lang

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Articles 22
Citations 312
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Recent Articles
1.
Lang S, Manning N, Armstrong N, Misso K, Allen A, Di Nisio M, et al.
Curr Med Res Opin . 2012 Feb; 28(3):351-70. PMID: 22292469
Objective: To assess the efficacy of tirofiban in comparison to usual care or other GPIIb/IIIa antagonists (eptifibatide and abciximab). Results were analysed by drug administration with planned percutaneous coronary intervention...
2.
Pearson J, Hughes S, Chambers K, Lang S
Cell Death Differ . 2008 Dec; 16(3):475-82. PMID: 19096393
There are two predominant theories for lumen formation in tissue morphogenesis: cavitation driven by cell death, and membrane separation driven by epithelial polarity. To define the mechanism of lumen formation...
3.
Lang S, Frame F, Collins A
J Pathol . 2008 Dec; 217(2):299-306. PMID: 19040209
Despite the discovery over 60 years ago by Huggins and Hodges that prostate cancers respond to androgen deprivation therapy, hormone-refractory prostate cancer remains a major clinical challenge. There is now...
4.
Scott L, Clarke N, Sharrard M, George N, Lang S
Prostate Cancer Prostatic Dis . 2002 Dec; 3(S1):S8. PMID: 12497118
No abstract available.
5.
Hart C, Scott L, Bagley S, Bryden A, Clarke N, Lang S
Br J Cancer . 2002 Apr; 86(7):1136-42. PMID: 11953862
Prostate cancers ability to invade and grow in bone marrow stroma is thought to be due in part to degradative enzymes. The formation of prostate skeletal metastases have been reproduced...
6.
Lang S, Stark M, Collins A, Paul A, Stower M, Maitland N
Cell Growth Differ . 2001 Dec; 12(12):631-40. PMID: 11751458
To reproduce the structural and functional differentiation of human prostatic acini in vivo, prostatic epithelial and stromal cells derived from human primary cultures were cocultured in Matrigel. In the absence...
7.
Lang S, Sharrard R, Stark M, Villette J, Maitland N
Br J Cancer . 2001 Aug; 85(4):590-9. PMID: 11506501
Normal (PNT2-C2) and metastatic (PC-3) prostate cell lines were grown in Matrigel to observe the effects on morphology and phenotype in comparison to monolayer culture. In monolayer cultures, PNT2-C2 showed...
8.
Scott L, Clarke N, George N, Shanks J, Testa N, Lang S
Br J Cancer . 2001 May; 84(10):1417-23. PMID: 11355957
Prostate cancer shows a propensity to form secondary tumours within the bone marrow. Such tumours are the major cause of mortality in this disease. We have developed an in vitro...
9.
Lang S, Stower M, Maitland N
Br J Cancer . 2000 Mar; 82(4):990-7. PMID: 10732776
To study the effects of stromal epithelial cell interactions on prostate cancer metastasis, we have used primary human prostatic stromal cells derived from malignant and non-malignant tissues and established epithelial...
10.
Lang S, Clarke N, George N, Testa N
Clin Exp Metastasis . 1999 Nov; 17(4):333-40. PMID: 10545020
Prostate cancer metastases form selectively in the bone marrow. Previously we demonstrated motility was important for the formation of primary prostatic epithelial cell colonies in bone marrow stroma (BMS) co-culture....