S G Tevosian
Overview
Explore the profile of S G Tevosian including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
625
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Recent Articles
1.
Tevosian S
Sex Dev
. 2012 Aug;
7(1-3):33-45.
PMID: 22846624
During embryonic development, ovarian somatic cells embark on a course that is separate from male somatic cells and from indifferent precursor cells. While the former aspect of ovarian development is...
2.
Manuylov N, Zhou B, Ma Q, Fox S, Pu W, Tevosian S
Dev Biol
. 2011 Mar;
353(2):229-41.
PMID: 21385577
Assembly of functioning testis and ovary requires a GATA4-FOG2 transcriptional complex. To define the separate roles for GATA4 and FOG2 proteins in sexual development of the testis we have ablated...
3.
Manuylov N, Smagulova F, Tevosian S
Oncogene
. 2007 Feb;
26(36):5204-13.
PMID: 17310981
The critical role for GATA family proteins in maintaining the normal (non-transformed) cell state is corroborated by the recent findings of mutations or methylation in GATA genes both in primary...
4.
Sampson E, Haque Z, Ku M, Tevosian S, Albanese C, Pestell R, et al.
EMBO J
. 2001 Aug;
20(16):4500-11.
PMID: 11500377
In certain cancers, constitutive Wnt signaling results from mutation in one or more pathway components. The result is the accumulation and nuclear localization of beta-catenin, which interacts with the lymphoid...
5.
Fossett N, Tevosian S, Gajewski K, Zhang Q, Orkin S, Schulz R
Proc Natl Acad Sci U S A
. 2001 Jun;
98(13):7342-7.
PMID: 11404479
Friend of GATA (FOG) proteins regulate GATA factor-activated gene transcription. During vertebrate hematopoiesis, FOG and GATA proteins cooperate to promote erythrocyte and megakaryocyte differentiation. The Drosophila FOG homologue U-shaped (Ush)...
6.
Tevosian S, Deconinck A, Tanaka M, Schinke M, Litovsky S, Izumo S, et al.
Cell
. 2000 Jul;
101(7):729-39.
PMID: 10892744
We disrupted the FOG-2 gene in mice to define its requirement in vivo. FOG-2(-/-) embryos die at midgestation with a cardiac defect characterized by a thin ventricular myocardium, common atrioventricular...
7.
Deconinck A, Mead P, Tevosian S, Crispino J, Katz S, Zon L, et al.
Development
. 2000 Apr;
127(10):2031-40.
PMID: 10769228
Members of the GATA family of zinc-finger transcription factors have critical roles in a variety of cell types. GATA-1, GATA-2 and GATA-3 are required for proliferation and differentiation of several...
8.
Gartel A, Goufman E, Tevosian S, Shih H, Yee A, Tyner A
Oncogene
. 1999 Feb;
17(26):3463-9.
PMID: 10030670
The Cdk inhibitor p21(WAF1/CIP1) is a negative regulator of the cell cycle, although its expression is induced by a number of mitogens that promote cell proliferation. We have found that...
9.
Tevosian S, Deconinck A, Cantor A, Rieff H, Fujiwara Y, Corfas G, et al.
Proc Natl Acad Sci U S A
. 1999 Feb;
96(3):950-5.
PMID: 9927674
GATA factors are transcriptional regulatory proteins that play critical roles in the differentiation of multiple cell types in both vertebrates and invertebrates. Recent evidence suggests that the biological activities of...
10.
Shih H, Tevosian S, Yee A
Mol Cell Biol
. 1998 Jul;
18(8):4732-43.
PMID: 9671483
Differentiation is a coordinated process of irreversible cell cycle exit and tissue-specific gene expression. To probe the functions of the retinoblastoma protein (RB) family in cell differentiation, we isolated HBP1...