S G N Grant
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Explore the profile of S G N Grant including associated specialties, affiliations and a list of published articles.
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16
Citations
754
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Recent Articles
1.
Coba M, Ramaker M, Ho E, Thompson S, Komiyama N, Grant S, et al.
Sci Rep
. 2018 Feb;
8(1):2281.
PMID: 29396406
The scaffold protein DLGAP1 is localized at the post-synaptic density (PSD) of glutamatergic neurons and is a component of supramolecular protein complexes organized by PSD95. Gain-of-function variants of DLGAP1 have...
2.
van de Lagemaat L, Stanford L, Pettit C, Strathdee D, Strathdee K, Elsegood K, et al.
Genes Brain Behav
. 2016 Nov;
16(4):409-418.
PMID: 27886459
Behavioural analysis of mice carrying engineered mutations is widely used to identify roles of specific genes in components of the mammalian behavioural repertoire. The reproducibility and robustness of phenotypic measures...
3.
Lalo U, Palygin O, Verkhratsky A, Grant S, Pankratov Y
Sci Rep
. 2016 Sep;
6:33609.
PMID: 27640997
Recent studies highlighted the importance of astrocyte-secreted molecules, such as ATP, for the slow modulation of synaptic transmission in central neurones. Biophysical mechanisms underlying the impact of gliotransmitters on the...
4.
Nithianantharajah J, McKechanie A, Stewart T, Johnstone M, Blackwood D, St Clair D, et al.
Sci Rep
. 2015 Oct;
5:14613.
PMID: 26423861
Development of effective therapies for brain disorders has been hampered by a lack of translational cognitive testing methods. We present the first example of using the identical touchscreen-based cognitive test...
5.
Fitzgerald P, Pinard C, Camp M, Feyder M, Sah A, Bergstrom H, et al.
Mol Psychiatry
. 2015 Apr;
20(7):913.
PMID: 25824301
No abstract available.
6.
Hill W, Davies G, van de Lagemaat L, Christoforou A, Marioni R, Fernandes C, et al.
Transl Psychiatry
. 2014 Jan;
4:e341.
PMID: 24399044
Differences in general cognitive ability (intelligence) account for approximately half of the variation in any large battery of cognitive tests and are predictive of important life events including health. Genome-wide...
7.
McMahon A, Barnett M, OLeary T, Stoney P, Collins M, Papadia S, et al.
Nat Commun
. 2012 Jun;
3:900.
PMID: 22692543
Alternative promoter usage and alternative splicing enable diversification of the transcriptome. Here we demonstrate that the function of Synaptic GTPase-Activating Protein (SynGAP), a key synaptic protein, is determined by the...
8.
Kirov G, Pocklington A, Holmans P, Ivanov D, Ikeda M, Ruderfer D, et al.
Mol Psychiatry
. 2011 Nov;
17(2):142-53.
PMID: 22083728
A small number of rare, recurrent genomic copy number variants (CNVs) are known to substantially increase susceptibility to schizophrenia. As a consequence of the low fecundity in people with schizophrenia...
9.
Grant S
Cold Spring Harb Symp Quant Biol
. 2009 Dec;
74:249-57.
PMID: 19955255
Beneath the complexity of the human brain are molecular principles shaped by evolution explaining the origins of the behavioral repertoire. The role of the nervous system is to provide a...
10.
Park C, Elgersma Y, Grant S, Morrison J
Neuroscience
. 2007 Dec;
151(1):43-55.
PMID: 18082335
N-methyl-d-aspartate receptors (NMDARs) are critical determinants of bidirectional synaptic plasticity, however, studies of NMDAR function have been based primarily on pharmacological and electrophysiological manipulations, and it is still debated whether...