S F Hackett
Overview
Explore the profile of S F Hackett including associated specialties, affiliations and a list of published articles.
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Articles
29
Citations
874
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Recent Articles
1.
Shen J, Dong A, Hackett S, Bell W, Green W, Campochiaro P
Histol Histopathol
. 2007 Aug;
22(12):1301-8.
PMID: 17701910
Epidemiologic studies have suggested that elderly patients who consumed diets rich in antioxidants throughout their lives are less likely to be afflicted with age-related macular degeneration (AMD). This led to...
2.
Shen J, Samul R, Silva R, Akiyama H, Liu H, Saishin Y, et al.
Gene Ther
. 2005 Oct;
13(3):225-34.
PMID: 16195704
In this study, we used small interfering RNA (siRNA) directed against vascular endothelial growth factor receptor 1 (vegfr1) mRNA to investigate the role of VEGFR1 in ocular neovascularization (NV). After...
3.
Nambu H, Nambu R, Oshima Y, Hackett S, Okoye G, Wiegand S, et al.
Gene Ther
. 2004 Mar;
11(10):865-73.
PMID: 15042118
Several retinal and choroidal diseases are potentially treatable by intraocular delivery of genes whose products may counter or neutralize abnormal gene expression that occurs as part of the diseases. However,...
4.
Seo M, Okamoto N, Vinores M, Vinores S, Hackett S, Yamada H, et al.
Am J Pathol
. 2000 Sep;
157(3):995-1005.
PMID: 10980138
Expression of platelet-derived growth factor (PDGF)-A and PDGF-B is increased in patients with proliferative retinopathies in which traction retinal detachments occur. Previous studies have demonstrated that increased expression of PDGF-A...
5.
Hackett S, Ozaki H, Strauss R, Wahlin K, Suri C, Maisonpierre P, et al.
J Cell Physiol
. 2000 Jul;
184(3):275-84.
PMID: 10911358
Vascular development in the embryo requires coordinated signaling through several endothelial cell-specific receptors; however, it is not known whether this is also required later during retinal vascular development or as...
6.
Mathura Jr J, Jafari N, Chang J, Hackett S, Wahlin K, Della N, et al.
Invest Ophthalmol Vis Sci
. 2000 Feb;
41(2):592-600.
PMID: 10670493
Purpose: To determine the relative level and localization of bone morphogenetic protein (BMP-4 mRNA in the retina and retinal pigmented epithelium (RPE) under normal and pathologic conditions, to seek clues...
7.
Yamada H, Yamada E, Hackett S, Ozaki H, Okamoto N, Campochiaro P
J Cell Physiol
. 1999 Apr;
179(2):149-56.
PMID: 10199554
Mice or humans with photoreceptor degenerations experience permeability and dropout of retinal capillaries. Loss of photoreceptors results in decreased oxygen usage and thinning of the retina with increased oxygen delivery...
8.
Ozaki H, Yu A, Della N, Ozaki K, Luna J, Yamada H, et al.
Invest Ophthalmol Vis Sci
. 1999 Jan;
40(1):182-9.
PMID: 9888442
Purpose: Hypoxia inducible factor-1 (HIF-1) is a transcription factor composed of HIF-1alpha and HIF-1beta subunits. HIF-1 transactivates multiple genes whose products play key roles in oxygen homeostasis, including vascular endothelial...
9.
Hackett S, Friedman Z, Freund J, Schoenfeld C, Curtis R, DiStefano P, et al.
Brain Res
. 1998 May;
789(2):201-12.
PMID: 9573364
There is evidence suggesting reciprocal trophic interactions between photoreceptors and the retinal pigmented epithelium (RPE), but the factors involved have not been identified. In this study, we investigated the hypothesis...
10.
Chen Y, Hackett S, Schoenfeld C, Vinores M, Vinores S, Campochiaro P
Br J Ophthalmol
. 1998 Mar;
81(10):919-26.
PMID: 9486038
Aims/background: Epiretinal membranes (ERMs) arise from a variety of causes or, in some cases, for unknown reasons. Once established, ERMs tend to progress, becoming more extensive and exerting increasing traction...