S Eccles
Overview
Explore the profile of S Eccles including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
38
Citations
307
Followers
0
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Recent Articles
11.
O-Charoenrat P, Rhys-Evans P, Eccles S
Anticancer Res
. 2001 Aug;
21(3B):1953-63.
PMID: 11497283
Ten human head and neck squamous carcinoma (HNSCC) cell lines were established in order to study the role of c-erbB signaling pathways in HNSCC progression. Five cell lines were derived...
12.
O-Charoenrat P, Rhys-Evans P, Eccles S
Int J Cancer
. 2000 Nov;
88(5):759-65.
PMID: 11072245
We recently reported that multiple c-erbB ligands differentially modulate in vitro proliferation, invasion and expression of matrix metalloproteinases in human head and neck squamous carcinoma cells (HNSCC). In order to...
13.
O-Charoenrat P, Rhys-Evans P, Modjtahedi H, Court W, Box G, Eccles S
Int J Cancer
. 2000 Apr;
86(3):307-17.
PMID: 10760816
Numerous reports have shown an association between overexpression of the epidermal growth factor receptor (EGFR), and poor prognosis in head and neck squamous cell carcinomas (HNSCC), however, the underlying mechanisms...
14.
Eccles S, House A, Knapp P
J Neurol Neurosurg Psychiatry
. 1999 Aug;
67(1):125-6.
PMID: 10454876
No abstract available.
15.
Mistry P, Plumb J, Eccles S, Watson S, Dale I, Ryder H, et al.
Br J Cancer
. 1999 Apr;
79(11-12):1672-8.
PMID: 10206276
Overexpression of P-glycoprotein (P-gp) is a potential cause of multidrug resistance (MDR) in tumours. We have previously reported that XR9051 (N-(4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydro-2-isoquinolyl)ethyl)phe nyl)-3-((3Z,6Z)-6-benzylidene-1-methyl-2,5-dioxo-3-pipera zinylidene)methylbenzamide) is a potent and specific inhibitor of...
16.
Smith T, Eccles S, Box G, Titley J, Leach M, McCready V
Anticancer Res
. 1996 May;
16(3B):1389-92.
PMID: 8694506
Rat sarcoma cells were grown in vitro in tissue culture medium (DMEM) supplemented with 10% foetal calf serum for 5 to 8 days followed by serum withdrawal to produce populations...
17.
Modjtahedi H, Hickish T, Nicolson M, Moore J, Styles J, Eccles S, et al.
Br J Cancer
. 1996 Jan;
73(2):228-35.
PMID: 8546911
The purpose of this study was to determine the effect of the first rat monoclonal antibody (MAb ICR62) to the epidermal growth factor receptor (EGFR) in a phase I clinical...
18.
Tacconi L, Eccles S, Johnston F, Symon L
Surg Neurol
. 1995 Apr;
43(4):389-92.
PMID: 7792711
Mycosis fungoides is a rare malignant T-cell lymphoma, involving mainly the skin. It can, in 50%-75% of cases, involve visceral organs and, in 11%-14% of cases, metastasize to the central...
19.
Carnochan P, Trivedi M, Young H, Eccles S, Potter G, Haynes B, et al.
J Nucl Biol Med (1991)
. 1994 Dec;
38(4 Suppl 1):96-8.
PMID: 7632777
With a view to evaluating the role of PET imaging in early clinical studies of new anticancer drugs, we are investigating the recently developed antiestrogen compound pyrrolidino-4-iodo-tamoxifen (idoxifene). Preliminary experimental...
20.
Modjtahedi H, Eccles S, Sandle J, Box G, Titley J, Dean C
Cancer Res
. 1994 Apr;
54(7):1695-701.
PMID: 8137284
We have carried out an immunohistochemical investigation of xenografts of epidermal growth factor receptor (EGFR)-overexpressing tumors that have been induced to regress by treatment with rat monoclonal antibodies (mAbs) to...