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S D Varfolomeev

Explore the profile of S D Varfolomeev including associated specialties, affiliations and a list of published articles. Areas
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Articles 154
Citations 224
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Recent Articles
1.
Varfolomeev S, Panin A, Semenova N, Ublinskiy M, Akhadov T, Bykov V, et al.
Russ Chem Bull . 2022 May; 71(3):591-594. PMID: 35495106
A kinetic study of the effect of thermoheliox (inhalation of a helium and oxygen mixture, 70 °C) on the functional hemodynamics of the human brain by functional magnetic resonance imaging...
2.
Nemukhin A, Grigorenko B, Lushchekina S, Varfolomeev S
Russ Chem Bull . 2022 Jan; 70(11):2084-2089. PMID: 35068913
Molecular modeling tools were applied to design a potential covalent inhibitor of the main protease (M) of the SARS-CoV-2 virus and to investigate its interaction with the enzyme. The compound...
3.
Varfolomeev S, Zhuravel S, Panin A, Shogenova L, Bykov V, Tsybenova S, et al.
Dokl Biochem Biophys . 2021 Mar; 496(1):44-47. PMID: 33689074
The high efficiency of using thermoheliox (inhalation with a high-temperature mixture of helium and oxygen) in the treatment of patients affected by COVID-19 was shown. The dynamics of accumulation of...
4.
Polyakov I, Kniga A, Grigorenko B, Nemukhin A, Varfolomeev S
Dokl Biochem Biophys . 2020 Dec; 495(1):334-337. PMID: 33368046
Three-dimensional full-atom model of the enzyme complex with acetyl-CoA and substrate was constructed on the basis of the primary sequence of amino acid residues of N-acetyl glutamate synthase. Bioinformatics approaches...
5.
Varfolomeev S, Panin A, Ryabokon A, Kozyr A, Kononikhin A, Shogenova L, et al.
Ter Arkh . 2020 Dec; 92(6):69-72. PMID: 33346495
Aim: Conducting a pilot study to assess the effect of thermal heliox on the state of the respiratory tract by studying of the exhaled breath condensate protein composition before the...
6.
Varfolomeev S, Panin A, Ryabokon A, Kozyr A, Kononikhin A, Shogenova L, et al.
Russ Chem Bull . 2020 Oct; 69(9):1816-1818. PMID: 33071535
The proteome of exhaled breath condensate was analyzed by mass spectrometry before and immediately after the thermoheliox procedure and after a 3 h relaxation. The major part of the proteome...
7.
Varfolomeev S, Panin A, Bykov V, Tsybenova S
Russ Chem Bull . 2020 Oct; 69(9):1811-1815. PMID: 33071534
A kinetic model is proposed to describe the key features of development of an acute viral infection, accumulation of antibodies, and immune response in the human body. The general features...
8.
Varfolomeev S, Panin A, Bykov V, Tsybenova S, Shogenova L, Chuchalin A
Russ Chem Bull . 2020 Aug; 69(6):1179-1184. PMID: 32834708
A kinetic model of the development of acute viral infection is proposed and the dynamic behavior of key variables, including the concentrations of viral particles, infected cells, and pathogenic microorganisms,...
9.
Varfolomeev S, Bykov V, Tsybenova S
Dokl Biochem Biophys . 2020 Jul; 492(1):147-151. PMID: 32632593
In the framework of the kinetic model, the functioning of the cholinergic synapse is considered. The results of mathematical modeling of changes in the level of acetylcholine, induced pH impulse,...
10.
Varfolomeev S, Bykov V, Tsybenova S
Dokl Biochem Biophys . 2020 Jun; 491(1):85-88. PMID: 32483758
A kinetic model describing the dynamics of synaptic "discharge" taking into account the kinetics of the injection of the neurotransmitter into the synaptic cleft, the pH-dependence of the catalytic activity...