S D Handran
Overview
Explore the profile of S D Handran including associated specialties, affiliations and a list of published articles.
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Articles
4
Citations
257
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0
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Recent Articles
1.
Hyrc K, Handran S, Rothman S, Goldberg M
J Neurosci
. 1997 Sep;
17(17):6669-77.
PMID: 9254679
Cytosolic calcium ([Ca2+]i) is an important mediator of neuronal signal transduction, participating in diverse biochemical reactions that elicit changes in synaptic efficacy, metabolic rate, and gene transcription. Excessive [Ca2+]i also...
2.
Handran S, Werth J, DeVivo D, Rothman S
Neurobiol Dis
. 1997 Jan;
3(4):287-98.
PMID: 9173926
Mitochondrial encephalomyopathies arise from mutations in the mitochondrial or nuclear genome and result in defective energy metabolism. Investigation of cellular pathophysiology in these disorders has been limited to nonneuronal explant...
3.
Dugan L, Sensi S, Canzoniero L, Handran S, Rothman S, Lin T, et al.
J Neurosci
. 1995 Oct;
15(10):6377-88.
PMID: 7472402
Increasing evidence suggests that glutamate neurotoxicity is partly mediated by reactive oxygen species, formed as a consequence of several processes, including arachidonic acid metabolism and nitric oxide production. Here we...
4.
Moudy A, Handran S, Goldberg M, Ruffin N, Karl I, DeVivo D, et al.
Proc Natl Acad Sci U S A
. 1995 Jan;
92(3):729-33.
PMID: 7846043
Patients with several inherited human encephalomyopathies exhibit systemic and neurological symptoms in association with specific mitochondrial mutations. The mechanisms by which these mitochondrial mutations result in cellular injury have not...