S D Dertinger
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Explore the profile of S D Dertinger including associated specialties, affiliations and a list of published articles.
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22
Citations
202
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Recent Articles
1.
Palermo C, Hernando J, Dertinger S, Kende A, Gasiewicz T
Chem Res Toxicol
. 2003 Jul;
16(7):865-72.
PMID: 12870889
Previous investigations have implicated green tea to exert chemopreventive effects in animal models of chemical carcinogenesis, including polycyclic aryl hydrocarbon-induced cancers. In an effort to understand the compound(s) responsible for...
2.
Torous D, Hall N, Dertinger S, Diehl M, Cederbrant K, Sandelin K, et al.
Environ Mol Mutagen
. 2001 Jul;
38(1):59-68.
PMID: 11473389
This laboratory previously described a single-laser flow cytometric method, which effectively resolves micronucleated erythrocyte populations in rodent peripheral blood samples. Even so, the rarity and variable size of micronuclei make...
3.
Nazarenko D, Dertinger S, Gasiewicz T
Toxicol Sci
. 2001 May;
61(2):256-64.
PMID: 11353134
The aryl-hydrocarbon receptor (AhR) is a ligand-activated transcription factor that is a member of the bHLH-PAS family of proteins. The highest-affinity ligand of this receptor is 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), which is...
4.
Nazarenko D, Dertinger S, Gasiewicz T
Biotechniques
. 2001 Apr;
30(4):776-7, 780-1.
PMID: 11314260
beta-galactosidase (beta-gal), the product of the E. coli LacZ gene, has been used extensively as a reporter in numerous systems. Until recently, the most commonly used method of detecting beta-gal...
5.
Dertinger S, Nazarenko D, Silverstone A, Gasiewicz T
Carcinogenesis
. 2001 Feb;
22(1):171-7.
PMID: 11159756
This laboratory has previously reported data suggesting that aryl hydrocarbon receptor (AhR) signaling may have a net potentiating effect on the DNA damaging potential of cigarette smoke. The experiments described...
6.
Dertinger S, Lantum H, Silverstone A, Gasiewicz T
Biochem Pharmacol
. 2000 May;
60(2):189-96.
PMID: 10825463
This laboratory has studied a number of flavone derivatives for aryl hydrocarbon receptor (AhR) agonist and antagonist potential using cell-free and cell culture systems. The current report extends these investigations...
7.
Hayashi M, MacGregor J, Gatehouse D, Adler I, BLAKEY D, Dertinger S, et al.
Environ Mol Mutagen
. 2000 Mar;
35(3):234-52.
PMID: 10737958
An expert working group on the in vivo micronucleus assay, formed as part of the International Workshop on Genotoxicity Test Procedures (IWGTP), discussed protocols for the conduct of established and...
8.
Torous D, Dertinger S, Hall N, Tometsko C
Mutat Res
. 2000 Mar;
465(1-2):91-9.
PMID: 10708974
Micronuclei (MN) are routinely enumerated in mouse peripheral blood to index genotoxicity. Recent data from the Collaborative Study Group for the Micronucleus Test (CSGMT) [CSGMT (The Collaborative Study Group for...
9.
Dertinger S, Torous D, Hall N, Tometsko C, Gasiewicz T
Mutat Res
. 2000 Jan;
464(2):195-200.
PMID: 10648906
A procedure for optimizing the configuration of flow cytometers for enumerating micronucleated erythrocytes is described. The method is based on the use of a biological model for micronucleated erythrocytes, the...
10.
Henry E, Kende A, Rucci G, Totleben M, Willey J, Dertinger S, et al.
Mol Pharmacol
. 1999 Apr;
55(4):716-25.
PMID: 10101030
Previous analyses suggested that potent aryl hydrocarbon receptor (AhR) antagonists were planar, with a lateral electron-rich center. To further define structural requirements and mechanism for antagonism, ten additional flavone derivatives...