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S C Straley

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Articles 57
Citations 2492
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Recent Articles
1.
Leigh S, Forman S, Perry R, Straley S
Microb Pathog . 2005 Jun; 38(5-6):259-66. PMID: 15925275
The signature-tagged mutagenesis (STM) method was applied in a protocol designed to identify genes required for Yersinia pestis invasion into epithelial cells. A library of 3060 mutants of Y. pestis...
2.
Hines J, Skrzypek E, Kajava A, Straley S
Microb Pathog . 2001 Apr; 30(4):193-209. PMID: 11312613
The plague virulence protein YopM of Yersinia pestis KIM5 belongs to the large family of leucine-rich repeat (LRR) proteins. The only activity demonstrated so far for YopM is thrombin-binding, which...
3.
Cowan C, Jones H, Kaya Y, Perry R, Straley S
Infect Immun . 2000 Jul; 68(8):4523-30. PMID: 10899851
The causative agent of plague, Yersinia pestis, is regarded as being noninvasive for epithelial cells and lacks the major adhesins and invasins of its enteropathogenic relatives Yersinia enterocolitica and Yersinia...
4.
Fields K, Nilles M, Cowan C, Straley S
Infect Immun . 1999 Sep; 67(10):5395-408. PMID: 10496922
Yersinia pestis, the etiologic agent of plague, secretes a set of environmentally regulated, plasmid pCD1-encoded virulence proteins termed Yops and V antigen (LcrV) by a type III secretion mechanism (Ysc)....
5.
Fields K, Straley S
Infect Immun . 1999 Aug; 67(9):4801-13. PMID: 10456934
Yersinia pestis is the causative agent of bubonic plague and possesses a set of plasmid-encoded, secretable virulence proteins termed LcrV and Yops which are essential for survival in mammalian hosts....
6.
Payne P, Straley S
J Bacteriol . 1999 Apr; 181(9):2852-62. PMID: 10217778
The Yersinia pestis low-Ca2+ response stimulon is responsible for the environmentally regulated expression and secretion of antihost proteins (V antigen and Yops). We have previously shown that yscO encodes a...
7.
Skrzypek E, Cowan C, Straley S
Mol Microbiol . 1999 Feb; 30(5):1051-65. PMID: 9988481
The YopM virulence protein of Yersinia pestis has been described as binding human alpha-thrombin and inhibiting thrombin-induced platelet aggregation in vitro. However, recent studies have shown that a YopM-CyaA fusion...
8.
Perry R, Straley S, Fetherston J, Rose D, Gregor J, Blattner F
Infect Immun . 1998 Sep; 66(10):4611-23. PMID: 9746557
The low-Ca2+-response (LCR) plasmid pCD1 of the plague agent Yersinia pestis KIM5 was sequenced and analyzed for its genetic structure. pCD1 (70,509 bp) has an IncFIIA-like replicon and a SopABC-like...
9.
Payne P, Straley S
J Bacteriol . 1998 Jul; 180(15):3882-90. PMID: 9683485
The Yersinia pestis low-Ca2+ response stimulon is responsible for the temperature- and Ca2+-regulated expression and secretion of plasmid pCD1-encoded antihost proteins (V antigen and Yops). We have previously shown that...
10.
Nilles M, Fields K, Straley S
J Bacteriol . 1998 Jun; 180(13):3410-20. PMID: 9642196
Yersinia pestis expresses a set of secreted proteins called Yops and the bifunctional LcrV, which has both regulatory and antihost functions. Yops and LcrV expression and the activity of the...