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S C Sim

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Articles 8
Citations 223
Followers 0
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Recent Articles
1.
Jukic M, Opel N, Strom J, Carrillo-Roa T, Miksys S, Novalen M, et al.
Mol Psychiatry . 2017 Apr; 22(8):1224. PMID: 28416806
This corrects the article DOI: 10.1038/mp.2016.204.
2.
Jukic M, Opel N, Strom J, Carrillo-Roa T, Miksys S, Novalen M, et al.
Mol Psychiatry . 2016 Nov; 22(8):1155-1163. PMID: 27895323
The polymorphic CYP2C19 enzyme metabolizes psychoactive compounds and is expressed in the adult liver and fetal brain. Previously, we demonstrated that the absence of CYP2C19 is associated with lower levels...
3.
Kalman L, Agundez J, Appell M, Black J, Bell G, Boukouvala S, et al.
Clin Pharmacol Ther . 2015 Oct; 99(2):172-85. PMID: 26479518
This article provides nomenclature recommendations developed by an international workgroup to increase transparency and standardization of pharmacogenetic (PGx) result reporting. Presently, sequence variants identified by PGx tests are described using...
4.
Persson A, Sim S, Virding S, Onishchenko N, Schulte G, Ingelman-Sundberg M
Mol Psychiatry . 2013 Jul; 19(6):733-41. PMID: 23877834
Selective serotonin reuptake inhibitors, tricyclic antidepressants, various psychoactive drugs, as well as endogenous steroids and cannabinoid-like compounds are metabolized by the polymorphic cytochrome P450 2C19 (CYP2C19). Absence of this enzyme...
5.
Sim S, Kacevska M, Ingelman-Sundberg M
Pharmacogenomics J . 2012 Oct; 13(1):1-11. PMID: 23089672
Interindividual differences in drug disposition are important causes for adverse drug reactions and lack of drug response. The majority of phase I and phase II drug-metabolizing enzymes (DMEs) are polymorphic...
6.
Curley J, Sim S, Warnke S, Leong S, Barker R, Jung G
Theor Appl Genet . 2005 Sep; 111(6):1107-17. PMID: 16133316
Gray leaf spot (GLS) is a serious fungal disease caused by Magnaporthe grisea, recently reported on perennial ryegrass (Lolium perenne L.), an important turf grass and forage species. This fungus...
7.
Gamkhar S, Sim S
J Health Polit Policy Law . 2002 Feb; 26(6):1261-90. PMID: 11831580
Are the federal Alcohol and Drug Abuse (ADA) block grant funds substituting for or supplementing state and local government spending on substance abuse? Using panel data on state and local...
8.
Eng P, Allen D, Chew S, Monteiro E, Sim S
Ann Acad Med Singap . 1992 Nov; 21(6):843-5. PMID: 1338271
Respiratory infections occur commonly in patients with advanced human immunodeficiency virus (HIV) infection. Prompt accurate diagnosis is essential as many of the various available therapies have significant toxicities. We describe...