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S C Schafer

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Articles 14
Citations 453
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Recent Articles
1.
Thomalla D, Beckmann L, Grimm C, Oliverio M, Meder L, Herling C, et al.
Blood . 2022 Jun; 140(20):2113-2126. PMID: 35704690
The BCL2 inhibitor venetoclax has been approved to treat different hematological malignancies. Because there is no common genetic alteration causing resistance to venetoclax in chronic lymphocytic leukemia (CLL) and B-cell...
2.
Hagmeyer L, Tharun L, Schafer S, Hekmat K, Buttner R, Randerath W
Gen Thorac Cardiovasc Surg . 2017 Jun; 65(9):535-538. PMID: 28653299
Epithelial-myoepithelial carcinoma is a well differentiated malignant neoplasm, which originates from the salivary glands. The primary pulmonary manifestation is rare-about 30 cases have been reported worldwide. In the literature, anatomical...
3.
Sendi P, Meier R, Sonderegger B, Bonel H, Schafer S, Vogelin E
Neth J Med . 2014 Nov; 72(9):491-3. PMID: 25431395
Granulomatous infections are commonly associated with mycobacteria, brucellosis, actinomycosis, nocardiosis, spirochetes, and fungi. Rarely, granuloma formation is a host response to other bacterial infection. Osteomyelitis and osteitis that reactivate many...
4.
Buhl S, Neumann B, Schafer S, Severing A
Int J Comput Biol Drug Des . 2014 Jun; 7(2-3):259-77. PMID: 24878733
This paper presents a method of separating cells that are connected to each other forming clusters. The difference to many other publications covering similar topics is that the cell types...
5.
Salm F, Cwiek P, Ghosal A, Lucia Buccarello A, Largey F, Wotzkow C, et al.
Oncogene . 2012 Oct; 32(34):3944-53. PMID: 23027129
Chemotherapeutic drug resistance is one of the major causes for treatment failure in high-risk neuroblastoma (NB), the most common extra cranial solid tumor in children. Poor prognosis is typically associated...
6.
Fandel T, Pfnur M, Schafer S, Bacchetti P, Mast F, Corinth C, et al.
J Pathol . 2008 Aug; 216(2):193-200. PMID: 18683853
In the histomorphological grading of prostate carcinoma, pathologists have regularly assigned comparable scores for the architectural Gleason and the now-obsolete nuclear World Health Organization (WHO) grading systems. Although both systems...
7.
Schafer S, Wallerath T, Closs E, Schmidt C, Schwarz P, Forstermann U, et al.
Am J Physiol Heart Circ Physiol . 2004 Dec; 288(1):H436-44. PMID: 15598872
Long-term treatment with glucocorticoids is associated with mild to moderate hypertension. We reported previously that downregulation of endothelial NO synthase (eNOS) expression and activity is likely to contribute to this...
8.
Wallerath T, Witte K, Schafer S, Schwarz P, Prellwitz W, Wohlfart P, et al.
Proc Natl Acad Sci U S A . 1999 Nov; 96(23):13357-62. PMID: 10557325
Hypertension is a side effect of systemically administered glucocorticoids, but the underlying molecular mechanism remains poorly understood. Ingestion of dexamethasone by rats telemetrically instrumented increased blood pressure progressively over 7...
9.
Max M, Schafer S, Gaughan A, Smoller B, Gracely R, Dubner R
Clin Pharmacol Ther . 1990 Mar; 47(3):305-12. PMID: 2178851
Desipramine has the least anticholinergic and sedative effects of the first generation tricyclic antidepressant agents, but its pain-relieving potential has received little study. Other antidepressant agents--notably amitriptyline--are known to ameliorate...
10.
Hargreaves K, Troullos E, Dionne R, Schmidt E, Schafer S, Joris J
Clin Pharmacol Ther . 1988 Dec; 44(6):613-21. PMID: 3197362
Bradykinin is a potent pain-producing substance, yet little is known about its role in inflammation. The present study measured circulating levels of immunoreactive bradykinin in a clinical model of acute...