S C De Smedt
Overview
Explore the profile of S C De Smedt including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
54
Citations
1079
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Wels M, Roels D, Raemdonck K, De Smedt S, Sauvage F
J Control Release
. 2021 Apr;
333:560-578.
PMID: 33857565
Biologics, like peptides, proteins and nucleic acids, have proven to be promising drugs for the treatment of numerous diseases. However, besides the off label use of the monoclonal antibody bevacizumab...
2.
Opening doors with ultrasound and microbubbles: Beating biological barriers to promote drug delivery
Deprez J, Lajoinie G, Engelen Y, De Smedt S, Lentacker I
Adv Drug Deliv Rev
. 2021 Mar;
172:9-36.
PMID: 33705877
Apart from its clinical use in imaging, ultrasound has been thoroughly investigated as a tool to enhance drug delivery in a wide variety of applications. Therapeutic ultrasound, as such or...
3.
Laser-induced vapor nanobubbles improve diffusion in biofilms of antimicrobial agents for wound care
Teirlinck E, Fraire J, Van Acker H, Wille J, Swimberghe R, Brans T, et al.
Biofilm
. 2021 Jan;
1:100004.
PMID: 33447791
Being responsible for delayed wound healing, the presence of biofilms in infected wounds leads to chronic, and difficult to treat infections. One of the reasons why antimicrobial treatment often fails...
4.
Roovers S, Deprez J, Priwitaningrum D, Lajoinie G, Rivron N, Declercq H, et al.
J Control Release
. 2019 Nov;
316:79-92.
PMID: 31676384
Ultrasound-triggered drug-loaded microbubbles have great potential for drug delivery due to their ability to locally release drugs and simultaneously enhance their delivery into the target tissue. We have recently shown...
5.
Remaut K, Symens N, Lucas B, Demeester J, De Smedt S
J Control Release
. 2014 Jan;
179:1-9.
PMID: 24462902
The delivery of plasmid DNA remains hard to achieve, especially due to the presence of the nuclear membrane barrier. During cell division, however, the nuclear membrane is temporarily disassembled. We...
6.
Ragelle H, Riva R, Vandermeulen G, Naeye B, Pourcelle V, Le Duff C, et al.
J Control Release
. 2014 Jan;
176:54-63.
PMID: 24389132
This study aims at developing chitosan-based nanoparticles suitable for an intravenous administration of small interfering RNA (siRNA) able to achieve (i) high gene silencing without cytotoxicity and (ii) stability in...
7.
Lentacker I, De Cock I, Deckers R, De Smedt S, Moonen C
Adv Drug Deliv Rev
. 2013 Nov;
72:49-64.
PMID: 24270006
In the past two decades, research has underlined the potential of ultrasound and microbubbles to enhance drug delivery. However, there is less consensus on the biophysical and biological mechanisms leading...
8.
Al Soraj M, He L, Peynshaert K, Cousaert J, Vercauteren D, Braeckmans K, et al.
J Control Release
. 2012 Apr;
161(1):132-41.
PMID: 22465675
Cell penetrating peptides (CPPs) have been extensively studied as vectors for cellular delivery of therapeutic macromolecules. It is widely accepted that they can enter cells directly across the plasma membrane...
9.
Naeye B, Raemdonck K, Remaut K, Demeester J, De Smedt S
Curr Top Med Chem
. 2011 Dec;
12(2):89-96.
PMID: 22196275
Over the last decade, considerable effort has been put in the implementation of RNA interference (RNAi) as a treatment for various disorders. As RNAi occurs in the cytoplasm of cells,...
10.
Van de Ven H, Vermeersch M, Vandenbroucke R, Matheeussen A, Apers S, Weyenberg W, et al.
J Drug Target
. 2011 Nov;
20(2):142-54.
PMID: 22080813
Drug delivery systems present an opportunity to potentiate the therapeutic effect of antileishmanial drugs. Colloidal carriers are rapidly cleared by the phagocytic cells of the reticuloendothelial system (RES), rendering them...