S B Joseph
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Explore the profile of S B Joseph including associated specialties, affiliations and a list of published articles.
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10
Citations
1165
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Recent Articles
1.
Maher S, Bakowski M, Vantaux A, Flannery E, Andolina C, Gupta M, et al.
bioRxiv
. 2023 Feb;
PMID: 36778461
Radical cure of malaria must include elimination of quiescent 'hypnozoite' forms in the liver; however, the only FDA-approved treatments are contraindicated in many vulnerable populations. To identify new drugs and...
2.
Hu Y, Li K, Swahn H, Ordoukhanian P, Head S, Natarajan P, et al.
Osteoarthritis Cartilage
. 2022 Nov;
31(2):199-212.
PMID: 36354073
Objective: Transcriptomic changes in joint tissues during the development of osteoarthritis (OA) are of interest for the discovery of biomarkers and mechanisms of disease. The objective of this study was...
3.
Joseph S, Kirkpatrick M
J Evol Biol
. 2008 Mar;
21(3):773-80.
PMID: 18312560
The [PSI(+)] prion in yeast has been shown to improve short-term growth in some environments, but its effects on rates of adaptation have not been assessed before now. We adapted...
4.
Laffitte B, Joseph S, Walczak R, Pei L, Wilpitz D, Collins J, et al.
Mol Cell Biol
. 2001 Oct;
21(22):7558-68.
PMID: 11604492
Previous work has implicated the nuclear receptors liver X receptor alpha (LXR alpha) and LXR beta in the regulation of macrophage gene expression in response to oxidized lipids. Macrophage lipid...
5.
Lee R, Kertesz N, Joseph S, Jegalian A, Wu H
Blood
. 2001 Aug;
98(5):1408-15.
PMID: 11520789
Erythropoiesis occurs in 2 distinct waves during embryogenesis: the primitive wave in the extra-embryonic yolk sac (YS) followed by the definitive wave in the fetal liver and spleen. Even though...
6.
Chawla A, Boisvert W, Lee C, Laffitte B, Barak Y, Joseph S, et al.
Mol Cell
. 2001 Feb;
7(1):161-71.
PMID: 11172721
Previous work has implicated PPAR gamma in the regulation of CD36 expression and macrophage uptake of oxidized LDL (oxLDL). We provide evidence here that in addition to lipid uptake, PPAR...
7.
Laffitte B, REPA J, Joseph S, Wilpitz D, Kast H, Mangelsdorf D, et al.
Proc Natl Acad Sci U S A
. 2001 Jan;
98(2):507-12.
PMID: 11149950
Apolipoprotein E (apoE) secreted by macrophages in the artery wall exerts an important protective effect against the development of atherosclerosis, presumably through its ability to promote lipid efflux. Previous studies...
8.
Venkateswaran A, Laffitte B, Joseph S, Mak P, Wilpitz D, Edwards P, et al.
Proc Natl Acad Sci U S A
. 2000 Oct;
97(22):12097-102.
PMID: 11035776
LXR alpha is a nuclear receptor that has previously been shown to regulate the metabolic conversion of cholesterol to bile acids. Here we define a role for this transcription factor...
9.
Joseph S, Miner K, Croft M
Eur J Immunol
. 1998 Mar;
28(1):277-89.
PMID: 9485207
The role of antigen-presenting cell (APC)-derived cytokines in T cell activation is still controversial. Highly purified CD4 T cell populations of the naive and short-term Th1 and Th2 effector subsets...
10.
Croft M, Joseph S, Miner K
J Immunol
. 1997 Oct;
159(7):3257-65.
PMID: 9317124
Tolerance is thought to occur when Ag is presented to T cells in the absence of costimulatory interactions from APC accessory molecules. Of the professional APC, the resting B cell...