S A Lapa
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Explore the profile of S A Lapa including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
43
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0
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Recent Articles
1.
Shishkin I, Shtylev G, Barsky V, Lapa S, Zasedateleva O, Kuznetsova V, et al.
Mol Biol (Mosk)
. 2024 Dec;
58(3):469-481.
PMID: 39707857
A method has been developed for manufacturing biological microchips on an aluminum substrate with hydrophilic cells from brush copolymers with the formation of a matrix of cells using photolithography. The...
2.
Lapa S, Surzhikov S, Blagodatskikh S, Shershov V, Chudinov A
Mol Biol (Mosk)
. 2023 Jun;
57(3):539-545.
PMID: 37326059
A diagnostic system based on recombinase polymerase amplification (RPA) has been developed to identify six bacterial pathogens of human pneumonia. Species-specific primers have been designed and optimized to conduct a...
3.
Lapa S, Antipova O, Chudinov A
Mol Biol (Mosk)
. 2022 May;
56(3):521-527.
PMID: 35621110
A new method for evaluating the substrate efficiency of deoxynucleoside triphosphates containing functional groups for the selection of modified aptamers (mod-SELEX) is proposed. The method involves conducting three consecutive rounds...
4.
Lapa S, Volkova O, Kuznetsova V, Zasedatelev A, Chudinov A
Mol Biol (Mosk)
. 2022 Jan;
56(1):157-167.
PMID: 35082264
The substrate properties of nitrogen-base modified derivatives of purine and pyrimidine deoxynucleoside triphosphates during their simultaneous pairwise insertion into the growing DNA strand have been studied. Modified nucleotides were introduced...
5.
Lapa S, Miftakhov R, Klochikhina E, Ammur Y, Blagodatskikh S, Shershov V, et al.
Mol Biol
. 2021 Dec;
55(6):828-838.
PMID: 34955557
A prototype of a system for the detection of infectious human pneumonia pathogens based on multiplex solid-phase reverse transcription PCR (RT-PCR) was developed. Primers were designed to identify the DNA...
6.
Lapa S, Miftakhov R, Klochikhina E, Ammur Y, Blagodatskikh S, Shershov V, et al.
Mol Biol (Mosk)
. 2021 Nov;
55(6):944-955.
PMID: 34837698
A prototype of a system for the detection of infectious human pneumonia pathogens based on multiplex solid-phase reverse transcription PCR (RT-PCR) was developed. Primers were designed to identify the DNA...
7.
Lapa S, Klochikhina E, Miftakhov R, Zolotov A, Zasedatelev A, Chudinov A
Russ J Bioorg Chem
. 2020 Nov;
46(5):859-861.
PMID: 33132678
A multiplex PCR system has been developed and optimized for rapid detection of the five main pathogens of bacterial pneumonia. The system can be expanded to analyze viral pathogens of...
8.
Radko S, Lapa S, Chudinov A, Khmeleva S, Mannanova M, Kurbatov L, et al.
Biomed Khim
. 2019 Dec;
65(6):477-484.
PMID: 31876518
Using random (combinatorial) DNA-libraries with various degrees of diversity, it was shown that their amplification by polymerase chain reaction in real time resulted in appearance of a maximum on amplification...
9.
Lapa S, Pavlov A, Kuznetsova V, Shershov V, Spitsyn M, Guseinov T, et al.
Mol Biol (Mosk)
. 2019 Jun;
53(3):513-523.
PMID: 31184617
The effects of modified deoxyuridine triphosphates (mod-dUTPs) with different substituents at the C5 position of the pyrimidine cycle on the kinetics of PCR with Taq and Vent (exo-) DNA polymerases...
10.
Lapa S, Romashova K, Spitsyn M, Shershov V, Kuznetsova V, Guseinov T, et al.
Mol Biol (Mosk)
. 2019 Jan;
52(6):984-996.
PMID: 30633241
A modification of the enzymatic method for the preparation of combinatorial random DNA libraries, which combines amplification in isolated microvolumes with the simultaneous incorporation of modified nucleotides and subsequent separation...