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S A Fraser

Explore the profile of S A Fraser including associated specialties, affiliations and a list of published articles. Areas
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Articles 19
Citations 283
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Recent Articles
11.
Fraser S, Michalak M, Welch W, Hudig D
Biochem Cell Biol . 1999 Jun; 76(5):881-7. PMID: 10353724
Cytotoxic lymphocytes kill virally infected cells with specialized cytotoxic granules containing perforin, a protein that forms toxic pores in the target cell membrane. These specialized cytotoxic granules also contain calreticulin,...
12.
Andrin C, Pinkoski M, Burns K, Atkinson E, Krahenbuhl O, Hudig D, et al.
Biochemistry . 1998 Jul; 37(29):10386-94. PMID: 9671507
Calreticulin is a component of cytotoxic T-lymphocyte and NK lymphocyte granules. We report here that granule-associated calreticulin terminates with the KDEL endoplasmic reticulum retrieval amino acid sequence and somehow escapes...
13.
JACKSON D, Fraser S, Ni L, Kam C, Winkler U, Johnson D, et al.
J Med Chem . 1998 Jun; 41(13):2289-301. PMID: 9632362
Thirty-six new amino acid and peptidyl diphenyl phosphonate esters were synthesized and evaluated to identify potent and selective inhibitors for four trypsin-like proteases: lymphocyte granzymes A and K, human mast...
14.
Woodard S, Fraser S, Winkler U, JACKSON D, Kam C, POWERS J, et al.
J Immunol . 1998 May; 160(10):4988-93. PMID: 9590247
One mechanism of killing by cytotoxic lymphocytes involves the exocytosis of specialized granules. The released granules contain perforin, which assembles into pores in the membranes of cells targeted for death....
15.
Winkler U, Fraser S, Hudig D
Biochem Biophys Res Commun . 1997 Jul; 236(1):34-9. PMID: 9223421
Perforin is a 68 kD protein found in the granules of cytotoxic lymphocytes and is used by lymphocytes to form lethal pores in the membranes of the cells they kill....
16.
Dunnigan M, Fraser S, McIntosh W, Moseley H, Sumner D
Scott Med J . 1986 Jul; 31(3):144-9. PMID: 3798077
Vitamin D deficiency is common in the house-bound and institutionalised elderly population of Britain. A study of patients over 65 years discharged with a diagnosis of osteomalacia from Greater Glasgow...
17.
Smith D, Fraser S, WILSON G
Clin Endocrinol Metab . 1973 Jul; 2(2):333-54. PMID: 4548007
No abstract available.
18.
Fraser S, Anderson J, Smith D, WILSON G
Lancet . 1971 May; 1(7707):981-3. PMID: 4102450
No abstract available.
19.
Fraser S, WILSON G
Lancet . 1971 Apr; 1(7702):725-6. PMID: 4101429
No abstract available.