Ryunosuke Nakashima
Overview
Explore the profile of Ryunosuke Nakashima including associated specialties, affiliations and a list of published articles.
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Articles
12
Citations
71
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Recent Articles
1.
Takahashi N, Nakashima R, Nasu A, Hayashi M, Fujikawa H, Kawakami T, et al.
Antioxidants (Basel)
. 2024 Jan;
13(1).
PMID: 38247455
Chronic obstructive pulmonary disease (COPD) is a complex pulmonary condition characterized by bronchitis, emphysema, and mucus stasis. Due to the variability in symptoms among patients, traditional approaches to treating COPD...
2.
Nakashima R, Nohara H, Takahashi N, Nasu A, Hayashi M, Kishimoto T, et al.
J Pharmacol Sci
. 2022 May;
149(2):37-45.
PMID: 35512853
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of death in the world, and has no radical treatment. Inhibition of amiloride-sensitive epithelial sodium ion channel (ENaC) has...
3.
Fujikawa H, Sakamoto Y, Masuda N, Oniki K, Kamei S, Nohara H, et al.
Antioxidants (Basel)
. 2020 May;
9(5).
PMID: 32384764
The oxidant/antioxidant imbalance plays a pivotal role in the lung. Uric acid (UA), an endogenous antioxidant, is highly present in lung tissue, however, its impact on lung function under pathophysiological...
4.
Oniki K, Nohara H, Nakashima R, Obata Y, Muto N, Sakamoto Y, et al.
Sci Rep
. 2020 Apr;
10(1):5973.
PMID: 32249844
Oxidative stress and inflammation play a key role in the age-related decline in the respiratory function. Adipokine in relation to the metabolic and inflammatory systems is attracting growing interest in...
5.
Oniki K, Kawakami T, Nakashima A, Miyata K, Watanabe T, Fujikawa H, et al.
Sci Rep
. 2020 Mar;
10(1):4313.
PMID: 32152335
Melinjo seed extract (MSE) contains large amounts of polyphenols, including dimers of trans-resveratrol (e.g. gnetin C, L, gnemonoside A, B and D), and has been shown to potentially improve obesity....
6.
Fujikawa H, Kawakami T, Nakashima R, Nasu A, Kamei S, Nohara H, et al.
Biol Pharm Bull
. 2020 Feb;
43(4):725-730.
PMID: 32009028
Epithelial sodium channel (ENaC) is an amiloride-sensitive sodium ion channel that is expressed in epithelial tissues. ENaC overexpression and/or hyperactivation in airway epithelial cells cause sodium over-absorption and dysregulated ciliary...
7.
Nohara H, Nakashima R, Kamei S, Fujikawa H, Ueno-Shuto K, Kawakami T, et al.
Biochem Biophys Res Commun
. 2020 Jan;
524(2):332-339.
PMID: 31996306
Glucagon-like peptide-1 (GLP-1) is a gastrointestinal hormone that stimulates glucose-mediated insulin production by pancreatic beta cells. It is also associated with protective effects in multiple tissues. GLP-1 receptor is highly...
8.
Nakashima R, Kamei S, Nohara H, Fujikawa H, Maruta K, Kawakami T, et al.
J Pharmacol Sci
. 2019 Jun;
140(2):113-119.
PMID: 31248767
Pulmonary emphysema, inflammation and senescence-like phenotype are pathophysiological characteristics of chronic obstructive pulmonary disease (COPD). Recently, a murine model of COPD has been established by inducing airway-specific overexpression of epithelial...
9.
Chaudhary N, Ueno-Shuto K, Ono T, Ohira Y, Watanabe K, Nasu A, et al.
Biol Pharm Bull
. 2019 Jan;
42(3):489-495.
PMID: 30626802
Cystic fibrosis (CF), the most common lethal inherited disorder caused by mutation in the gene encoding the CF transmembrane regulator (CFTR), is characterized by chronic inflammation that ultimately leads to...
10.
Kamei S, Maruta K, Fujikawa H, Nohara H, Ueno-Shuto K, Tasaki Y, et al.
Biochem Biophys Res Commun
. 2019 Jan;
509(2):521-528.
PMID: 30598261
Cystic fibrosis transmembrane regulator (CFTR) is a cyclic AMP-dependent Cl channel, and its dysfunction, due to CFTR gene mutations, causes the lethal inherited disorder cystic fibrosis (CF). To date, widespread...