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Ryan van Luchene

Explore the profile of Ryan van Luchene including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 174
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Recent Articles
1.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs A, Smemo S, et al.
Am J Hum Genet . 2005 Dec; 78(1):78-88. PMID: 16385451
Strong evidence of linkage to late-onset Alzheimer disease (LOAD) has been observed on chromosome 10, which implicates a wide region and at least one disease-susceptibility locus. Although significant associations with...
2.
Li Y, Hollingworth P, Moore P, Foy C, Archer N, Powell J, et al.
Hum Mutat . 2005 Feb; 25(3):270-7. PMID: 15714520
Alzheimer disease (AD) is a complex neurodegenerative disorder predisposed by multiple genetic factors. Mutations in amyloid beta precursor protein (APP) are known to be associated with autosomal dominant, early onset...
3.
Li Y, Nowotny P, Holmans P, Smemo S, Kauwe J, Hinrichs A, et al.
Proc Natl Acad Sci U S A . 2004 Oct; 101(44):15688-93. PMID: 15507493
Although several genes have been implicated in the development of the early-onset autosomal dominant form of Alzheimer's disease (AD), the genetics of late-onset AD (LOAD) is complex. Loci on several...
4.
Li Y, Tacey K, Doil L, van Luchene R, Garcia V, Rowland C, et al.
Neurosci Lett . 2004 Aug; 366(3):268-71. PMID: 15288432
Genetic association of ABCA1 or the ATP-binding cassette A1 transporter with late-onset Alzheimer's disease (LOAD) has recently been proposed for a haplotype comprised of three single nucleotide polymorphisms (SNPs). We...