Ryan Shapiro
Overview
Explore the profile of Ryan Shapiro including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
15
Citations
249
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Vallee I, Shapiro R, Yang X
IUBMB Life
. 2025 Feb;
77(2):e70000.
PMID: 39994779
Oligomerization can influence the stability and activity of a protein. The majority of enzymes, including aminoacyl-tRNA synthetases, become catalytically active upon forming homodimers. Residues located at the dimerization interface are...
2.
Rhymes E, Simkin R, Qu J, Villarroel-Campos D, Surana S, Tong Y, et al.
Neurobiol Dis
. 2024 Apr;
195:106501.
PMID: 38583640
Charcot-Marie-Tooth disease (CMT) is a genetic peripheral neuropathy caused by mutations in many functionally diverse genes. The aminoacyl-tRNA synthetase (ARS) enzymes, which transfer amino acids to partner tRNAs for protein...
3.
Rhymes E, Simkin R, Qu J, Villarroel-Campos D, Surana S, Tong Y, et al.
bioRxiv
. 2024 Apr;
PMID: 38559020
Charcot-Marie-Tooth disease (CMT) is a genetic peripheral neuropathy caused by mutations in many functionally diverse genes. The aminoacyl-tRNA synthetase (ARS) enzymes, which transfer amino acids to partner tRNAs for protein...
4.
Jones J, Wei N, Cui H, Shi Y, Fu G, Rauniyar N, et al.
Cell Rep
. 2023 Jun;
42(6):112632.
PMID: 37314928
Various stress conditions are signaled through phosphorylation of translation initiation factor eukaryotic initiation factor 2α (eIF2α) to inhibit global translation while selectively activating transcription factor ATF4 to aid cell survival...
5.
Morodomi Y, Kanaji S, Sullivan B, Zarpellon A, Orje J, Won E, et al.
Proc Natl Acad Sci U S A
. 2022 Nov;
119(48):e2212659119.
PMID: 36409883
Platelets play a role not only in hemostasis and thrombosis, but also in inflammation and innate immunity. We previously reported that an activated form of tyrosyl-tRNA synthetase (YRS) has an...
6.
Kanaji S, Chen W, Morodomi Y, Shapiro R, Kanaji T, Yang X
Trends Biochem Sci
. 2022 Oct;
48(3):288-302.
PMID: 36280495
Antisynthetase syndrome (ASSD) is an autoimmune disease characterized by circulating autoantibodies against one of eight aminoacyl-tRNA synthetases (aaRSs). Although these autoantibodies are believed to play critical roles in ASSD pathogenesis,...
7.
Harrison L, Shapiro R, Johnson R
Facial Plast Surg
. 2020 Dec;
36(6):688-695.
PMID: 33368123
Nonsurgical facelifts are a term for a heterogeneous group of procedures used by physicians to improve facial rejuvenation without the use of operative techniques. Patients demand these services due to...
8.
Won E, Morodomi Y, Kanaji S, Shapiro R, Vo M, Orje J, et al.
Res Pract Thromb Haemost
. 2020 Nov;
4(7):1167-1177.
PMID: 33134783
Background: Tyrosyl-tRNA synthetase (YRS) belongs to the family of enzymes that catalyzes the tRNA aminoacylation reaction for protein synthesis, and it has been recently shown to exert noncanonical functions. Although...
9.
Kanaji T, Vo M, Kanaji S, Zarpellon A, Shapiro R, Morodomi Y, et al.
Proc Natl Acad Sci U S A
. 2018 Aug;
115(35):E8228-E8235.
PMID: 30104364
New mechanisms behind blood cell formation continue to be uncovered, with therapeutic approaches for hematological diseases being of great interest. Here we report an enzyme in protein synthesis, known for...
10.
Bates B, Wimalawansa S, Monson B, Rymer M, Shapiro R, Johnson R
J Reconstr Microsurg
. 2013 Sep;
29(9):615-8.
PMID: 24019174
The rat femoral artery (RFA) anastomosis model has been the gold standard in microsurgical simulation training. While effective, live animal use requires animal use committee regulation and costly maintenance. Our...