Ryan J Bourgo
Overview
Explore the profile of Ryan J Bourgo including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
219
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0
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Recent Articles
1.
Bourgo R, Singhal H, Greene G
Nat Commun
. 2016 Sep;
7:12893.
PMID: 27634217
Here we describe a sensitive and novel method of identifying endogenous DNA-DNA interactions. Capture of Associated Targets on CHromatin (CATCH) uses efficient capture and enrichment of specific genomic loci of...
2.
Singhal H, Greene M, Tarulli G, Zarnke A, Bourgo R, Laine M, et al.
Sci Adv
. 2016 Jul;
2(6):e1501924.
PMID: 27386569
The functional role of progesterone receptor (PR) and its impact on estrogen signaling in breast cancer remain controversial. In primary ER(+) (estrogen receptor-positive)/PR(+) human tumors, we report that PR reprograms...
3.
Hutcheson J, Bourgo R, Balaji U, Ertel A, Witkiewicz A, Knudsen E
Hepatology
. 2014 May;
60(4):1231-40.
PMID: 24824777
Unlabelled: Cancers mediated by viral etiology must exhibit deregulated cellular proliferation and evade immune recognition. The role of the retinoblastoma tumor suppressor (RB) pathway, which is lost at relatively high...
4.
Chapa J, Bourgo R, Greene G, Kulkarni S, An G
PLoS One
. 2013 May;
8(5):e64091.
PMID: 23704974
The study of the pathogenesis of breast cancer is challenged by the long time-course of the disease process and the multi-factorial nature of generating oncogenic insults. The characterization of the...
5.
Bourgo R, Thangavel C, Ertel A, Bergseid J, McClendon A, Wilkens L, et al.
Mol Cell
. 2011 Aug;
43(4):663-72.
PMID: 21855804
The LXCXE peptide motif facilitates interaction between the RB tumor suppressor and a large number of cellular proteins that are expected to impinge on diverse biological processes. In vitro and...
6.
McClendon A, Dean J, Ertel A, Fu Z, Rivadeneira D, Reed C, et al.
Gastroenterology
. 2011 Jun;
141(4):1439-50.
PMID: 21704587
Background & Aims: The tumor suppressors retinoblastoma (RB) and p53 are important regulators of the cell cycle. Although human cancer cells inactivate RB and p53 by many mechanisms, the cooperative...
7.
Bourgo R, Ehmer U, Sage J, Knudsen E
Mol Biol Cell
. 2011 Feb;
22(7):931-9.
PMID: 21289097
The integrity of the retinoblastoma tumor suppressor (RB) pathway is critical for restraining inappropriate proliferation and suppressing tumor development in a plethora of tissues. Here adenovirus-mediated RB deletion in the...
8.
Bourgo R, Siddiqui H, Fox S, Solomon D, Sansam C, Yaniv M, et al.
Mol Biol Cell
. 2009 May;
20(14):3192-9.
PMID: 19458193
Switch (SWI)/sucrose nonfermentable (SNF) is an evolutionarily conserved complex with ATPase function, capable of regulating nucleosome position to alter transcriptional programs within the cell. It is known that the SWI/SNF...
9.
Bourgo R, Braden W, Wells S, Knudsen E
Mol Carcinog
. 2008 May;
48(1):45-55.
PMID: 18506774
High-risk human papilloma virus (HPV) encodes two oncoproteins, E6 and E7, which are vital to viral replication and contribute to the development of cervical cancer. HPV16 E7 can target over...