Ruxandra F Sirbulescu
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Explore the profile of Ruxandra F Sirbulescu including associated specialties, affiliations and a list of published articles.
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32
Citations
506
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Recent Articles
1.
Sirbulescu R, Nicholson K, Kawai K, Hilton O, Sobell D, Jin G, et al.
FASEB J
. 2024 Jul;
38(13):e23796.
PMID: 38967302
Amyotrophic lateral sclerosis (ALS) is an orphan neurodegenerative disease. Immune system dysregulation plays an essential role in ALS onset and progression. Our preclinical studies have shown that the administration of...
2.
Aspden J, Murphy M, Kashlan R, Xiong Y, Poznansky M, Sirbulescu R
Front Cell Neurosci
. 2024 Jan;
17:1329823.
PMID: 38269112
B lymphocytes are immune cells studied predominantly in the context of peripheral humoral immune responses against pathogens. Evidence has been accumulating in recent years on the diversity of immunomodulatory functions...
3.
Dwyer L, Maheshwari S, Levy E, Poznansky M, Whalen M, Sirbulescu R
J Neuroinflammation
. 2023 May;
20(1):133.
PMID: 37259118
Traumatic brain injury (TBI) remains a major cause of death and severe disability worldwide. We found previously that treatment with exogenous naïve B cells was associated with structural and functional...
4.
Maheshwari S, Dwyer L, Sirbulescu R
Neurobiol Dis
. 2023 Mar;
180:106077.
PMID: 36914074
Acute injury to the central nervous system (CNS) remains a complex and challenging clinical need. CNS injury initiates a dynamic neuroinflammatory response, mediated by both resident and infiltrating immune cells....
5.
Sirbulescu R, Ilies I, Amelung L, Zupanc G
J Comp Physiol A Neuroethol Sens Neural Behav Physiol
. 2022 Nov;
208(5-6):671-706.
PMID: 36445471
In adult mammals, spontaneous repair after spinal cord injury (SCI) is severely limited. By contrast, teleost fish successfully regenerate injured axons and produce new neurons from adult neural stem cells...
6.
Dwyer L, Stowe A, Doyle K, Popovich P, Engler-Chiurazzi E, LeGuern C, et al.
FASEB J
. 2022 Jul;
36(8):e22459.
PMID: 35857314
No abstract available.
7.
Theocharidis G, Thomas B, Sarkar D, Mumme H, Pilcher W, Dwivedi B, et al.
Nat Commun
. 2022 Jan;
13(1):181.
PMID: 35013299
Diabetic foot ulceration (DFU) is a devastating complication of diabetes whose pathogenesis remains incompletely understood. Here, we profile 174,962 single cells from the foot, forearm, and peripheral blood mononuclear cells...
8.
Sirbulescu R, Mamidi A, Chan S, Jin G, Boukhali M, Sobell D, et al.
FASEB J
. 2021 Nov;
35(12):e22019.
PMID: 34792819
Exogenously applied mature naïve B220 /CD19 /IgM /IgD B cells are strongly protective in the context of tissue injury. However, the mechanisms by which B cells detect tissue injury and...
9.
Kawai K, Stowe A, Evans C, Sirbulescu R, Hanidziar D, Lee K, et al.
FASEB J
. 2021 Jul;
35(8):e21744.
PMID: 34224602
No abstract available.
10.
Dauth S, Rakov H, Sirbulescu R, Ilies I, Weber J, Batbajar Dugershaw B, et al.
Cell Mol Neurobiol
. 2019 Dec;
40(5):695-710.
PMID: 31808010
Cathepsin K deficiency in male mice (Ctsk) results in decreased numbers of hippocampal astrocytes and altered neuronal patterning as well as learning and memory deficits. Additionally, cathepsin K carries essential...