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Ruth M Klement

Explore the profile of Ruth M Klement including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 362
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Recent Articles
1.
Santoro F, Mayer D, Klement R, Warczok K, Stukalov A, Barlow D, et al.
Development . 2013 Feb; 140(6):1184-95. PMID: 23444351
The imprinted Airn macro long non-coding (lnc) RNA is an established example of a cis-silencing lncRNA. Airn expression is necessary to initiate paternal-specific silencing of the Igf2r gene, which is...
2.
Latos P, Pauler F, Koerner M, Senergin H, Hudson Q, Stocsits R, et al.
Science . 2012 Dec; 338(6113):1469-72. PMID: 23239737
Mammalian imprinted genes often cluster with long noncoding (lnc) RNAs. Three lncRNAs that induce parental-specific silencing show hallmarks indicating that their transcription is more important than their product. To test...
3.
Koerner M, Pauler F, Hudson Q, Santoro F, Sawicka A, Guenzl P, et al.
PLoS Genet . 2012 Mar; 8(3):e1002540. PMID: 22396659
A CpG island (CGI) lies at the 5' end of the Airn macro non-protein-coding (nc) RNA that represses the flanking Igf2r promoter in cis on paternally inherited chromosomes. In addition...