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Ruth J Davis

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Citations 357
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Recent Articles
1.
Davis R, Akst L, Allen C, Battafarano R, Born H, Bryson P, et al.
JAMA Otolaryngol Head Neck Surg . 2025 Jan; 151(3):263-267. PMID: 39847385
Importance: Airway stenosis is a rare but debilitating disorder that significantly degrades the quality of life in affected patients. Treatments are primarily surgical, and disease management lacks established medical therapies....
2.
Bowen A, Roitman A, Ring S, Francis D, Davis R, McCulloch T, et al.
Am J Otolaryngol . 2024 Dec; 46(1):104568. PMID: 39740535
Objective: Internal Superior laryngeal nerve (iSLN) injections with steroids and anesthetic for Unexplained Chronic Cough (UCC) was initially described as a unilateral injection. This study reports the safety profile and...
3.
Kreuser H, Fletcher K, Davis R
Ann Otol Rhinol Laryngol . 2024 Nov; 134(4):291-293. PMID: 39614754
Objectives: Vocal fold injection augmentation with hyaluronic acid (HA) fillers is a common treatment for glottic insufficiency. While generally well-tolerated, rare inflammatory reactions can occur in 3% to 5% of...
4.
Davis R, Talatala E, Wu H, Zhang Y, Park J, Gelbard A
Otolaryngol Head Neck Surg . 2024 Oct; 172(2):563-570. PMID: 39441651
Objective: Laryngotracheal stenosis (LTS) describes fibrotic airway obstruction that is life-threatening without treatment. Targeted therapies are needed as an adjunct to surgical management. We have previously observed the upregulation of...
5.
Clark E, Talatala E, Ye W, Davis R, Collins S, Hillel A, et al.
Laryngoscope . 2024 Mar; 134(7):3245-3252. PMID: 38450771
Objectives: Recent immunologic study of the adaptive immune repertoire in the subglottic airway demonstrated high-frequency T cell clones that do not overlap between individuals. However, the anatomic distribution and antigenic...
6.
Barrios E, Mazer M, McGonagill P, Bergmann C, Goodman M, Gould R, et al.
JCI Insight . 2023 Dec; 9(2). PMID: 38100268
BACKGROUNDSepsis remains a major clinical challenge for which successful treatment requires greater precision in identifying patients at increased risk of adverse outcomes requiring different therapeutic approaches. Predicting clinical outcomes and...
7.
Davis R, Shilts M, Strickland B, Rajagopala S, Das S, Wootten C, et al.
Otolaryngol Head Neck Surg . 2023 Nov; 170(3):977-980. PMID: 37933740
The objective of this study was to characterize mucosal microbial shifts in patients with acute laryngeal injury (ALgI) after intubation. This cross-sectional study included 20 patients with ALgI who underwent...
8.
Clark E, Talatala E, Ye W, Davis R, Collins S, Hillel A, et al.
Laryngoscope . 2023 Oct; 134(4):1757-1764. PMID: 37787469
Objectives: Recent translational scientific efforts in subglottic stenosis (SGS) support a disease model where epithelial alterations facilitate microbiome displacement, dysregulated immune activation, and localized fibrosis. Given the observed immune cell...
9.
Talatala E, Clark E, Ye W, Davis R, Hillel A, Collins S, et al.
Laryngoscope . 2023 Jun; 133(12):3506-3511. PMID: 37382162
Objectives: Idiopathic subglottic stenosis (iSGS) is an unexplained progressive fibrosis of the upper airway. iSGS almost exclusively affects women; as a result, female hormones (estrogen and progesterone) have been proposed...
10.
Motz K, Lina I, Samad I, Murphy M, Duvvuri M, Davis R, et al.
JCI Insight . 2023 May; 8(11). PMID: 37159282
Laryngotracheal stenosis (LTS) is pathologic fibrotic narrowing of the larynx and trachea characterized by hypermetabolic fibroblasts and CD4+ T cell-mediated inflammation. However, the role of CD4+ T cells in promoting...