Ruth Conde-Garrosa
Overview
Explore the profile of Ruth Conde-Garrosa including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
553
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0
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Recent Articles
1.
Hernandez-Garcia E, Cueto F, Cook E, Redondo-Urzainqui A, Charro-Zanca S, Robles-Vera I, et al.
Cell Mol Immunol
. 2022 Jan;
19(2):260-275.
PMID: 34983945
Conventional dendritic cells (cDCs) scan and integrate environmental cues in almost every tissue, including exogenous metabolic signals. While cDCs are critical in maintaining immune balance, their role in preserving energy...
2.
Cueto F, Del Fresno C, Brandi P, Combes A, Hernandez-Garcia E, Sanchez-Paulete A, et al.
J Immunother Cancer
. 2021 May;
9(5).
PMID: 33980589
Background: Conventional type 1 dendritic cells (cDC1s) are central to antitumor immunity and their presence in the tumor microenvironment associates with improved outcomes in patients with cancer. DNGR-1 (CLEC9A) is...
3.
Khouili S, Cook E, Hernandez-Garcia E, Martinez-Lopez M, Conde-Garrosa R, Iborra S
Cell Rep
. 2020 Dec;
33(9):108468.
PMID: 33264612
Intracellular pathogens have evolved strategies to evade detection by cytotoxic CD8 T lymphocytes (CTLs). Here, we ask whether Leishmania parasites trigger the SHP-1-FcRγ chain inhibitory axis to dampen antigen cross-presentation...
4.
Acin-Perez R, Iborra S, Marti-Mateos Y, Cook E, Conde-Garrosa R, Petcherski A, et al.
Nat Metab
. 2020 Sep;
2(9):974-988.
PMID: 32943786
Proinflammatory macrophages are key in the development of obesity. In addition, reactive oxygen species (ROS), which activate the Fgr tyrosine kinase, also contribute to obesity. Here we show that ablation...
5.
Wculek S, Amores-Iniesta J, Conde-Garrosa R, Khouili S, Melero I, Sancho D
J Immunother Cancer
. 2019 Apr;
7(1):100.
PMID: 30961656
Background: The manipulation of dendritic cells (DCs) for cancer vaccination has not reached its full potential, despite the revolution in cancer immunotherapy. DCs are fundamental for CD8+ T cell activation,...
6.
Martinez-Lopez M, Iborra S, Conde-Garrosa R, Mastrangelo A, Danne C, Mann E, et al.
Immunity
. 2019 Feb;
50(2):446-461.e9.
PMID: 30709742
Production of interleukin-17 (IL-17) and IL-22 by T helper 17 (Th17) cells and group 3 innate lymphoid cells (ILC3s) in response to the gut microbiota ensures maintenance of intestinal barrier...
7.
Izquierdo H, Brandi P, Gomez M, Conde-Garrosa R, Priego E, Enamorado M, et al.
Cell Rep
. 2018 Aug;
24(7):1738-1746.
PMID: 30110631
The rapid transit from hypoxia to normoxia in the lung that follows the first breath in newborn mice coincides with alveolar macrophage (AM) differentiation. However, whether sensing of oxygen affects...
8.
Iborra S, Martinez-Lopez M, Cueto F, Conde-Garrosa R, Del Fresno C, Izquierdo H, et al.
Immunity
. 2016 Oct;
45(4):788-801.
PMID: 27742545
C-type lectin receptors sense a diversity of endogenous and exogenous ligands that may trigger differential responses. Here, we have found that human and mouse Mincle bind to a ligand released...
9.
Iborra S, Martinez-Lopez M, Khouili S, Enamorado M, Cueto F, Conde-Garrosa R, et al.
Immunity
. 2016 Oct;
45(4):847-860.
PMID: 27692611
Despite the crucial role of tissue-resident memory T (Trm) cells in protective immunity, their priming remains poorly understood. Here, we have shown differential priming requirements for Trm versus circulating memory...
10.
Blanco-Menendez N, Del Fresno C, Fernandes S, Calvo E, Conde-Garrosa R, Kerr W, et al.
J Immunol
. 2015 Sep;
195(9):4466-4478.
PMID: 26416276
Dectin-1 (Clec7a) is a paradigmatic C-type lectin receptor that binds Syk through a hemITAM motif and couples sensing of pathogens such as fungi to induction of innate responses. Dectin-1 engagement...