Ruth C Borghaei
Overview
Explore the profile of Ruth C Borghaei including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
8
Citations
100
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Seutter S, Winfield J, Esbitt A, Snyder S, Magner A, Kim K, et al.
Int Immunopharmacol
. 2019 Dec;
78:105920.
PMID: 31810887
Periodontitis is a common chronic inflammatory condition that results in increased levels of inflammatory cytokines and inflammatory mediators. In addition to oral disease and tooth loss, it also causes low-grade...
2.
Borghaei R, Gorski G, Seutter S, Chun J, Khaselov N, Scianni S
Biochem Biophys Res Commun
. 2016 Feb;
471(4):503-9.
PMID: 26891870
Matrix metalloproteinases (MMPs) have both protective and pathological roles in inflammation, and transcriptional mechanisms are important in regulating physiological levels to maintain health. Zinc-binding protein-89 (ZBP-89) is a transcription factor...
3.
Chambers M, Kirkpatrick G, Evans M, Gorski G, Foster S, Borghaei R
Exp Cell Res
. 2013 Apr;
319(10):1398-408.
PMID: 23608488
Matrix metalloproteinase-3 (MMP-3) over-expression is associated with tissue destruction in the context of chronic inflammation. Previous studies showed that IL-4 inhibits induction of MMP-3 by IL-1β, and suggested that AP-1...
4.
Borghaei R, Chambers M
Pathol Lab Med Int
. 2010 Aug;
1:7-12.
PMID: 20686646
Zinc-binding protein-89 (ZBP-89; ZNF148, BERF-1, BFCOL-1) is a zinc-finger transcription factor of the Kruppel family. It has been shown to regulate the expression of a number of genes, acting as...
5.
Borghaei R, Gorski G, Javadi M
Biochem Biophys Res Commun
. 2009 Mar;
382(2):269-73.
PMID: 19275880
A 5T/6T polymorphism in the human MMP-3 promoter affects gene expression and impacts the risk and/or severity of various pathological conditions. Chromatin immunoprecipitation (ChIP) in human fibroblasts homozygous for the...
6.
Stewart D, Javadi M, Chambers M, Gunsolly C, Gorski G, Borghaei R
BMC Mol Biol
. 2007 Feb;
8:12.
PMID: 17319946
Background: Interleukin 4 (IL-4) has been shown to suppress interleukin-1 (IL-1) induced expression of matrix metalloproteinase-3 (MMP-3) in human synovial and gingival fibroblasts, but the mechanism of suppression has not...
7.
Borghaei R, Rawlings Jr P, Javadi M, Woloshin J
Biochem Biophys Res Commun
. 2004 Mar;
316(1):182-8.
PMID: 15003528
A 5T/6T polymorphic site in the matrix metalloproteinase-3 (MMP-3) promoter has been identified as a repressor element involved in inhibiting induction of MMP-3 transcription by interleukin 1; and the 6T...
8.
Daghigh F, Borghaei R, Thornton R, Bee J
J Periodontol
. 2002 May;
73(4):392-400.
PMID: 11990440
Background: Although nitric oxide (NO) synthesis is increased in periodontal disease (PD), little is known about the possible sources of production by gingival tissues. In fact, gingival tissues from patients...