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Ruslana Tytarenko

Explore the profile of Ruslana Tytarenko including associated specialties, affiliations and a list of published articles. Areas
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Articles 16
Citations 416
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Recent Articles
1.
Boyle E, Deshpande S, Tytarenko R, Ashby C, Wang Y, Bauer M, et al.
Nat Commun . 2021 Jan; 12(1):293. PMID: 33436579
Smoldering myeloma (SMM) is associated with a high-risk of progression to myeloma (MM). We report the results of a study of 82 patients with both targeted sequencing that included a...
2.
Roy Choudhury S, Ashby C, Tytarenko R, Bauer M, Wang Y, Deshpande S, et al.
J Hematol Oncol . 2020 Aug; 13(1):108. PMID: 32762714
Background: Multiple Myeloma (MM) is a hematological malignancy with genomic heterogeneity and poor survival outcome. Apart from the central role of genetic lesions, epigenetic anomalies have been identified as drivers...
3.
Udaondo Z, Jenjaroenpun P, Wongsurawat T, Meyers E, Anderson C, Lopez J, et al.
Open Forum Infect Dis . 2020 Jun; 7(6):ofaa180. PMID: 32550237
In this work, we report 2 cases of vancomycin-resistant bacteremia with development of daptomycin resistance in 2 patients with acute myeloid leukemia and myelodysplastic syndrome. Mutations related to daptomycin-nonsusceptible phenotype...
4.
Jenjaroenpun P, Wongsurawat T, Udaondo Z, Anderson C, Lopez J, Mohan M, et al.
Microbiol Resour Announc . 2020 Feb; 9(6). PMID: 32029568
Here, we present complete genome sequences of four isolates, obtained from two patients with apparent vancomycin-resistant bacteremia; these isolates also carried two mutations known to be associated with daptomycin resistance....
5.
Udaondo Z, Wongsurawat T, Jenjaroenpun P, Anderson C, Lopez J, Mohan M, et al.
Microbiol Resour Announc . 2019 Apr; 8(15). PMID: 30975810
Vancomycin-resistant (VREfm) is a major cause of nosocomial infections of the bloodstream and urinary tract. Here, we report the draft genome sequences of 48 vancomycin-resistant isolates recovered from inpatients exhibiting...
6.
Battachariyya S, Tytarenko R, Heuck C, Greally J, Verma A
Methods Mol Biol . 2018 May; 1792:167-177. PMID: 29797259
Here we describe a method for genome wide investigation of methylation and hydroxymethylation status of cytosines. This protocol is an improvement of the HELP-tagging protocol previously described by Suzuki et...
7.
Rasche L, Angtuaco E, Alpe T, Gershner G, McDonald J, Samant R, et al.
Blood . 2018 May; 132(1):59-66. PMID: 29784643
Spatial intratumor heterogeneity is frequently seen in multiple myeloma (MM) and poses a significant challenge for risk classifiers, which rely on tumor samples from the iliac crest. Because biopsy-based assessment...
8.
Morgan G, He J, Tytarenko R, Patel P, Stephens O, Zhong S, et al.
Leukemia . 2018 Apr; 32(11):2435-2444. PMID: 29654269
Chromosomal rearrangements that result in oncogenic kinase activation are present in many solid and hematological malignancies, but none have been reported in multiple myeloma (MM). Here we analyzed 1421 samples...
9.
Pawlyn C, Loehr A, Ashby C, Tytarenko R, Deshpande S, Sun J, et al.
Leukemia . 2018 Feb; 32(7):1561-1566. PMID: 29467487
PARP inhibitors can induce synthetic lethality in tumors characterized by homologous recombination deficiency (HRD), which can be detected by evaluating genome-wide loss of heterozygosity (LOH). Multiple myeloma (MM) is a...
10.
Weinhold N, Ashby C, Rasche L, Chavan S, Stein C, Stephens O, et al.
Blood . 2016 Aug; 128(13):1735-44. PMID: 27516441
To elucidate the mechanisms underlying relapse from chemotherapy in multiple myeloma, we performed a longitudinal study of 33 patients entered into Total Therapy protocols investigating them using gene expression profiling,...