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Rupendra Shrestha

Explore the profile of Rupendra Shrestha including associated specialties, affiliations and a list of published articles. Areas
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Articles 62
Citations 758
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Recent Articles
1.
Srinivasan D, Subbarayan R, Krishnan M, Balakrishna R, Adtani P, Shrestha R, et al.
Radiat Environ Biophys . 2025 Jan; PMID: 39760753
Radiation therapy (RT) is fundamental to the fight against cancer because of its exceptional ability to target and destroy cancer cells. However, conventional radiation therapy can significantly affect the adjacent...
2.
Ferrena A, Zhang X, Shrestha R, Zheng D, Liu W
PLoS One . 2024 Oct; 19(10):e0308839. PMID: 39446806
How tissue-specific progenitor cells generate adult tissues is a puzzle in organogenesis. Using single-cell RNA sequencing of control and Six3 and Six6 compound-mutant mouse embryonic eyecups, we demonstrated that these...
3.
Haque S, Crawley K, Schofield D, Shrestha R, Davis R, Sue C
BMJ Neurol Open . 2024 Sep; 6(2):e000770. PMID: 39296527
Abstract: Background: Mitochondrial diseases often follow a chronic, multimorbid disease course in adults. Like other chronic conditions, mitochondrial diseases present a challenge to public and community health models and patients...
4.
Haque S, Crawley K, Schofield D, Shrestha R, Sue C
BMC Neurol . 2024 Sep; 24(1):343. PMID: 39272026
Background: Cascade testing can offer improved surveillance and timely introduction of clinical management for the at-risk biological relatives. Data on cascade testing and costs in mitochondrial diseases are lacking. To...
5.
Vijayakumar K, Manoharan D, Subbarayan R, Shrestha R, Harshavardhan S
Mol Biol Rep . 2024 Aug; 51(1):934. PMID: 39180671
Introduction: This study presents a Mammalian Linear Expression System (MLES), a linear covalently closed (LCC) vector based on pVAX-1. The purpose of this system was to improve gene expression in...
6.
Haque S, Crawley K, Davis R, Schofield D, Shrestha R, Sue C
BMJ Neurol Open . 2024 Jun; 6(1):e000717. PMID: 38868460
Background: Mitochondrial diseases in adults are generally chronic conditions with a wide spectrum of severity contributing to disease burden and healthcare resource utilisation. Data on healthcare resource utilisation in mitochondrial...
7.
Subbarayan R, Srinivasan D, Shadula Osmania S, Murugan Girija D, Ikhlas S, Srivastav N, et al.
Platelets . 2024 Jun; 35(1):2359028. PMID: 38832545
The purpose of this study is to investigate the molecular interactions and potential therapeutic uses of Eltrombopag (EPAG), a small molecule that activates the cMPL receptor. EPAG has been found...
8.
Schofield D, Lim K, Tanton R, Veerman L, Kelly S, Passey M, et al.
BMJ Open . 2024 May; 14(5):e076966. PMID: 38719327
Objectives: To estimate the economic burden of informal caregivers not in the labour force (NILF) due to caring for a person with arthritis in Australia, with projections of these costs...
9.
Subbarayan R, Murugan Girija D, Raja S, Krishnamoorthy A, Srinivasan D, Shrestha R, et al.
Mol Biol Rep . 2024 Apr; 51(1):570. PMID: 38658405
Introduction: Spinal cord injury (SCI) leads to significant destruction of nerve tissue, causing the degeneration of axons and the formation of cystic cavities. This study aimed to examine the characteristics...
10.
Schofield D, Shrestha R, Tan O, Lim K, Rajkumar R, West S, et al.
Int J Environ Res Public Health . 2024 Mar; 21(3). PMID: 38541298
Most of the studies on the cost of intellectual disability are limited to a healthcare perspective or cohorts composed of individuals where the etiology of the condition is a mixture...