Ruoyi Gu
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Explore the profile of Ruoyi Gu including associated specialties, affiliations and a list of published articles.
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6
Citations
25
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Recent Articles
1.
Tian G, He L, Gu R, Sun J, Chen W, Qian Y, et al.
Mol Med Rep
. 2022 Jan;
25(3).
PMID: 35059744
Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart malformation accounting for ~10% of cases. Although the pathogenesis of TOF is complex and largely unknown, epigenetics plays a...
2.
Zhu Y, Ye M, Xu H, Gu R, Ma X, Chen M, et al.
Mol Med Rep
. 2020 Oct;
22(5):4412-4422.
PMID: 33000281
Tetralogy of Fallot (TOF) is the most common form of cyanotic congenital heart disease (CHD). Although a lower methylation level of whole genome has been demonstrated in TOF patients, little...
3.
Li S, Liu S, Chen W, Yuan Y, Gu R, Song Y, et al.
Sci Rep
. 2018 Aug;
8(1):12386.
PMID: 30120289
Heterotaxy syndrome (HTX) is characterized by left-right (LR) asymmetry disturbances associated with severe heart malformations. However, the exact genetic cause of HTX pathogenesis remains unclear. The aim of this study...
4.
Gu R, Sheng W, Ma X, Huang G
Cardiol Young
. 2017 Dec;
28(3):397-402.
PMID: 29198211
Atrial septal defect is one of the most common CHD. The pathogenesis of atrial septal defect still remains unknown. Cx43 is the most prevalent connexin in the mammalian heart during...
5.
Gu R, Xu J, Lin Y, Sheng W, Ma D, Ma X, et al.
Sci Rep
. 2017 Sep;
7(1):10435.
PMID: 28874875
Abnormal level of Cx43 expression could result in CHD. Epigenetic modification and disease-associated, non-coding SNPs might influence gene transcription and expression. Our study aimed to determine the role of histone...
6.
Gu R, Xu J, Lin Y, Zhang J, Wang H, Sheng W, et al.
Pediatr Res
. 2016 Mar;
80(1):159-68.
PMID: 26991262
Introduction: Retinoic acid X receptor alpha (RXRα) and Connexin 43 (Cx43) both play a crucial role in cardiogenesis. However, little is known about the interplay mechanism between the RXRα and...