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Rumiana Tenchov

Explore the profile of Rumiana Tenchov including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 926
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Recent Articles
1.
Hughes K, Ganesan M, Tenchov R, Iyer K, Ralhan K, Diaz L, et al.
ACS Omega . 2025 Mar; 10(8):7530-7548. PMID: 40060806
Since their inception in the early 1960s, the use of nanoscale materials has progressed in leaps and bounds, and their role in diverse fields ranging from human health to energy...
2.
Tenchov R, Sasso J, Zhou Q
ACS Omega . 2025 Jan; 10(2):1864-1892. PMID: 39866628
Parkinson's disease (PD) is a progressive neurodegenerative disorder that primarily affects movement. It occurs due to a gradual deficit of dopamine-producing brain cells, particularly in the substantia nigra. The precise...
3.
Tenchov R, Hughes K, Ganesan M, Iyer K, Ralhan K, Lotti Diaz L, et al.
ACS Nano . 2025 Jan; 19(4):4011-4038. PMID: 39823199
Since their inception in the early 1960s, the development and use of nanoscale materials have progressed tremendously, and their roles in diverse fields ranging from human health to energy and...
4.
Tenchov R, Sasso J, Zhou Q
ACS Chem Neurosci . 2024 Oct; 15(21):3800-3827. PMID: 39392435
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and impaired daily functioning. The pathology of AD is marked by the accumulation of amyloid beta...
5.
Ivanov J, Tenchov R, Ralhan K, Iyer K, Agarwal S, Zhou Q
J Chem Inf Model . 2024 Sep; 64(19):7488-7502. PMID: 39289178
TBK1, or TANK-binding kinase 1, is an enzyme that functions as a serine/threonine protein kinase. It plays a crucial role in various cellular processes, including the innate immune response to...
6.
Tenchov R, Sasso J, Zhou Q
ACS Chem Neurosci . 2024 Jul; 15(15):2665-2694. PMID: 38996083
Polyglutamine (polyQ) diseases are a group of inherited neurodegenerative disorders caused by expanded cytosine-adenine-guanine (CAG) repeats encoding proteins with abnormally expanded polyglutamine tract. A total of nine polyQ disorders have...
7.
Iyer K, Ivanov J, Tenchov R, Ralhan K, Rodriguez Y, Sasso J, et al.
J Med Chem . 2024 May; 67(11):8519-8544. PMID: 38787632
In the ever-evolving landscape of cancer research, immuno-oncology stands as a beacon of hope, offering novel avenues for treatment. This study capitalizes on the vast repository of immuno-oncology-related scientific documents...
8.
Tenchov R, Sapra A, Sasso J, Ralhan K, Tummala A, Azoulay N, et al.
ACS Pharmacol Transl Sci . 2024 Mar; 7(3):586-613. PMID: 38481702
Cancer is one of the leading causes of death worldwide. Early cancer detection is critical because it can significantly improve treatment outcomes, thus saving lives, reducing suffering, and lessening psychological...
9.
Tenchov R, Sasso J, Wang X, Zhou Q
ACS Chem Neurosci . 2024 Jan; 15(3):408-446. PMID: 38214973
Aging is typified by a gradual loss of physiological fitness and accumulation of cellular damage, leading to deteriorated functions and enhanced vulnerability to diseases. Antiaging research has a long history...
10.
Tenchov R, Sasso J, Wang X, Zhou Q
ACS Chem Neurosci . 2023 Dec; 15(1):1-30. PMID: 38095562
Aging is a dynamic, time-dependent process that is characterized by a gradual accumulation of cell damage. Continual functional decline in the intrinsic ability of living organisms to accurately regulate homeostasis...