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Rufei Huang

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Articles 15
Citations 43
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Recent Articles
1.
Huang R, Xia H, Meng T, Fan Y, Tang X, Li Y, et al.
Theranostics . 2025 Feb; 15(6):2597-2623. PMID: 39990223
The generation of human testicular organoids from human induced pluripotent stem cells (hiPSCs) presents exciting opportunities for gonadal developmental biology, and reproductive disease modeling. However, creating organoids that closely mimic...
2.
Huang R, Xia H, Lin W, Wang Z, Li L, Deng J, et al.
Cells . 2024 Dec; 13(23). PMID: 39682764
Cancer treatments, including cytotoxic therapy, often result in male infertility, necessitating the development of safe and effective strategies to preserve male reproductive potential during chemotherapy. Notably, our study uncovers the...
3.
Liang J, Mei J, Chen D, Xiao Z, Hu M, Wei S, et al.
Mol Ther Nucleic Acids . 2024 Dec; 35(4):102369. PMID: 39640010
As delayed parenthood becomes more prevalent, understanding age-related testosterone decline and its impact on male fertility has gained importance. However, molecular mechanisms concerning testicular aging remain largely undiscovered. Our study...
4.
Wang Z, Chen H, Wang Y, Wu C, Ye T, Xia H, et al.
Int J Biol Macromol . 2024 Sep; 281(Pt 1):136064. PMID: 39341309
The integrity of the skin barrier is essential for maintaining skin health, with the stratum corneum and filaggrin 2 (FLG-2) playing a key role. FLG-2 deficiency or mutation has been...
5.
Li L, Liu Y, Chang R, Ye T, Li Z, Huang R, et al.
Antioxidants (Basel) . 2024 Aug; 13(8). PMID: 39199247
The epidermal barrier is vital for protecting the skin from environmental stressors and ultraviolet (UV) radiation. Filaggrin-2 (FLG2), a critical protein in the stratum corneum, plays a significant role in...
6.
Li L, Lin W, Wang Z, Huang R, Xia H, Li Z, et al.
Int J Mol Sci . 2024 Jun; 25(11). PMID: 38891991
The testes serve as the primary source of androgens and the site of spermatogenesis, with their development and function governed by hormonal actions via endocrine and paracrine pathways. Male fertility...
7.
Wei S, Li Z, Xia H, Wang Z, Deng J, Li L, et al.
Int J Biol Macromol . 2024 Apr; 268(Pt 1):131723. PMID: 38649072
Endometrial injury poses a significant challenge in tissue regeneration, with type III collagen (COL III) playing a pivotal role in maintaining endometrial integrity and facilitating repair. Our study explored the...
8.
Hu M, Li Z, Liu Y, Feng Y, Wang Z, Huang R, et al.
ACS Biomater Sci Eng . 2024 Apr; 10(5):3188-3202. PMID: 38592024
Chronic wound repair is a clinical treatment challenge. The development of multifunctional hydrogels is of great significance in the key aspects of treating chronic wounds, including reducing oxidative stress, promoting...
9.
Xiao Z, Liang J, Huang R, Chen D, Mei J, Deng J, et al.
Cells . 2024 Feb; 13(4. PMID: 38391926
Due to the increasing trend of delayed childbirth, the age-related decline in male reproductive function has become a widely recognized issue. Sertoli cells (SCs) play a vital role in creating...
10.
Deng J, Tang Y, Li L, Huang R, Wang Z, Ye T, et al.
Int J Mol Sci . 2023 Aug; 24(16). PMID: 37628741
The ovary is a highly susceptible organ to senescence, and granulosa cells (GCs) have a crucial role in oocyte development promotion and overall ovarian function maintenance. As age advances, GCs...