Rudimar Luiz Frozza
Overview
Explore the profile of Rudimar Luiz Frozza including associated specialties, affiliations and a list of published articles.
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12
Citations
1142
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Recent Articles
1.
Nobrega A, Pimentel R, Prado A, Garcia J, Frozza R, Bernardi A
Curr Cancer Drug Targets
. 2024 Feb;
24(6):579-594.
PMID: 38310461
Glioblastoma (GBM) stands as the most aggressive and lethal among the main types of primary brain tumors. It exhibits malignant growth, infiltrating the brain tissue, and displaying resistance toward treatment....
2.
Silva Y, Bernardi A, Frozza R
Front Endocrinol (Lausanne)
. 2020 Feb;
11:25.
PMID: 32082260
A substantial body of evidence supports that the gut microbiota plays a pivotal role in the regulation of metabolic, endocrine and immune functions. In recent years, there has been growing...
3.
Coutinho D, Pacheco M, Frozza R, Bernardi A
Int J Mol Sci
. 2018 Jun;
19(6).
PMID: 29925765
Inflammation is the principal response invoked by the body to address injuries. Despite inflammation constituting a crucial component of tissue repair, it is well known that unchecked or chronic inflammation...
4.
Pires E, Frozza R, Hoppe J, Menezes B, Salbego C
Brain Res
. 2014 Feb;
1557:26-33.
PMID: 24560603
Berberine is an alkaloid derived from herb the Berberis sp. and has long-term use in Oriental medicine. Studies along the years have demonstrated its beneficial effect in various neurodegenerative and...
5.
Stuepp C, Figueiro F, Mendes F, Braganhol E, Bernardi A, Frozza R, et al.
Anticancer Res
. 2013 Oct;
33(10):4463-8.
PMID: 24123016
Background/aim: Despite recent progress in glioblastoma treatment, prognosis is still poor. Monastrol is a kinesin spindle protein (KSP) inhibitor and anticancer effects for this molecule have been reported. Here we...
6.
Hoppe J, Frozza R, Pires E, Meneghetti A, Salbego C
Neurol Res
. 2013 Jul;
35(8):857-66.
PMID: 23816368
Objective: Accumulating evidence indicates that curcumin potently protects against beta-amyloid (Abeta) due to its oxygen free radicals scavenging and anti-inflammatory properties. However, cellular mechanisms that may underlie the neuroprotective effect...
7.
Horn A, Bernardi A, Frozza R, Grudzinski P, Hoppe J, de Souza L, et al.
Stem Cells Dev
. 2010 Oct;
20(7):1171-81.
PMID: 20955077
Cell therapy using bone marrow-derived mesenchymal stem cells (MSCs) seems to be a new alternative for the treatment of neurodegenerative diseases. Despite several promising results with their use, possible side...
8.
Hoppe J, Frozza R, Horn A, Comiran R, Bernardi A, Campos M, et al.
J Pineal Res
. 2010 Feb;
48(3):230-238.
PMID: 20136701
Alzheimer's disease (AD) is a progressive neurodegenerative disorder marked by accumulation of extracellular deposits of amyloid-beta (Abeta) peptide in brain regions that are important for memory and cognition. The buildup...
9.
Gerhardt D, Horn A, Gaelzer M, Frozza R, Delgado-Canedo A, Pelegrini A, et al.
Invest New Drugs
. 2008 Dec;
27(6):517-25.
PMID: 19050827
Malignant gliomas are the most common and devastating primary tumors of the central nervous system. Currently no efficient treatment is available. This study evaluated the effect and underlying mechanisms of...
10.
Horn A, Frozza R, Grudzinski P, Gerhardt D, Hoppe J, Bruno A, et al.
Neurosci Res
. 2008 Nov;
63(1):35-41.
PMID: 18977399
Cell therapy using bone marrow-derived mesenchymal stem cells (MSC) seems to be a new alternative for the treatment of neurological diseases, including stroke. In order to investigate the response of...